嗜酸性粒细胞在鼻息肉复发中的作用研究进展  

Advances in the role of eosinophils in the recurrence of nasal polyps

作　　者：廖敏 李双[1] 刘江怡 毛弈友 陈杰 陈卓[1] 杨玉成[1] Liao Min;Li Shuang;Liu Jiangyi;Mao Yiyou;Chen Jie;Chen Zhuo;Yang Yucheng(Department of Otolaryngology,First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆医科大学附属第一医院耳鼻咽喉科,重庆400016

出　　处：《国际耳鼻咽喉头颈外科杂志》2020年第2期96-99,共4页International Journal of Otolaryngology-Head and Neck Surgery

基　　金：国家自然科学基金(81970864)。

摘　　要：尽管有规范的药物治疗和外科治疗,慢性鼻-鼻窦炎伴鼻息肉(chronic rhinosinusitiswith nasal polyps,CRSwNP)仍然易复发且对患者的身心健康有严重影响,其中以嗜酸性粒细胞(eosinophil,Eos)浸润为特征的鼻息肉更容易复发且疗效更差.本文就Eos在CRSwNP复发中的作用,特别是局部炎症微环境对鼻息肉复发的影响做一综述,为提高鼻息肉的临床疗效、减少复发提供参考.Although chronic sinusitis with nasal polyps(CRSwNP)have standardized drug treatment and surgical treatment,they are still prone to recurrence and have a serious impact on the physical and mental health of patients,in which nasal polyps characterized by eosinophil infiltration are more likely to relapse and the curative effect is worse.This article reviews the role of Eos in the recurrenee of nasal polyps,especially the effect of local inflammatory microenvironment on the recurrence of nasal polyps,so as to provide reference for improving the clinical curative efleet and reducing the recurrenee of nasal polyps.

关 键 词：鼻窦炎 鼻息肉 嗜酸性细胞 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]