骨水泥分布对单侧穿刺经皮椎体成形治疗单节段骨质疏松性椎体压缩骨折后相邻椎体骨折的影响  

Effect of bone cement distribution on adjacent vertebral body fracture after unilateral percutaneous vertebroplasty for single segment osteoporotic vertebral compression fracture

作　　者：刘瑞祯 王望任 郝晨 梁冬牧 关海山[1] Liu Ruizhen;Wang Wangren;Hao Chen;Liang Dongmu;Guan Haishan(Department of Orthopedics,the Second Affiliated Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi Province,China)

机构地区：[1]山西医科大学第二附属医院骨科,山西省太原市030001

出　　处：《中国组织工程研究》2020年第28期4498-4504,共7页Chinese Journal of Tissue Engineering Research

摘　　要：背景:以往国内外关于经皮椎体成形后相邻椎体骨折的危险因素研究主要集中在骨水泥渗漏、骨水泥注入量、骨水泥黏度、椎体骨折数目及部位、椎体高度丢失和性别等方面。目的:预测与分析骨水泥分布对单侧穿刺经皮椎体成形治疗单节段骨质疏松性椎体压缩骨折后相邻椎体骨折的影响。方法:选择2017年6月至2018年6月山西医科大学第二附属医院收治的40例骨质疏松性椎体压缩骨折患者,其中男16例,女24例,年龄(71.4±5.3)岁,均进行单侧穿刺经皮椎体成形治疗。根据术后X射线片上骨水泥分布是否过椎体中线分为单侧组(13例13椎)和双侧组(27例27椎),依据骨水泥是否同时接触上下终板,单侧组分为A组(8例8椎,同时接触椎体上下终板)、B组(5例5椎,未同时接触上下终板),双侧组分为C组(11例11椎,同时接触椎体上下终板)、D组(16例16椎,未同时接触上下终板)。比较单、双侧组术前和术后1年的目测类比评分、Oswestry功能障碍指数评分及Cobb角,以及A、B、C、D组的患椎相邻上下椎体前、中柱压缩率和上下终板夹角改变程度。试验获得山西医科大学第二附属医院伦理委员会批准。结果与结论:①单、双侧组术后1年的目测类比评分、Oswestry功能障碍指数评分及Cobb角均较术前明显改善(P<0.001),两组组间上述指标比较差异均无显著性意义(P>0.05);②A、B、C、D组术后1年的病椎相邻椎体前缘与中柱压缩率均高于术前(P<0.05),4组术后1年的病椎相邻椎体上下终板夹角均大于术前(P<0.05);③以D组作为参考的无序多分类logistic回归分析显示,A组经皮椎体成形后相邻椎体压缩程度最大,是术后相邻椎体压缩改变的危险因素(P=0.003),B、C组不是经皮椎体成形后相邻椎体压缩改变的危险因素(P=0.065,0.660);④结果表明,经皮椎体成形后若骨水泥单侧分布且同时接近椎体上下终板,则相邻椎体骨折的趋势更�BACKGROUND: Previous studies on the risk factors of adjacent vertebral fractures after percutaneous vertebroplasty at home and abroad mainly focus on the leakage of bone cement, the amount of bone cement injected, the viscosity of bone cement, the number and location of vertebral fractures, the loss of vertebral height and sex. OBJECTIVE: To predict and analyze the influence of bone cement distribution on adjacent vertebral body fracture after unilateral percutaneous vertebroplasty for single segment osteoporotic vertebral compression fracture. METHODS: Forty patients with single segment osteoporotic vertebral compression fracture, including 16 males and 24 females, aged(71.4 ±5.3) years who received percutaneous vertebroplasty in the Second Affiliated Hospital of Shanxi Medical University from June 2017 to June 2018 were included in this study. These patients were divided into a unilateral group(13 vertebrae in 13 cases) and a bilateral group(27 vertebrae in 27 cases) according to the distribution of bone cement shown on X-ray film. Patients in the unilateral group were sub-divided into groups A(8 vertebrae in 8 cases, contacting the upper and lower endplates at the same time) and B(5 vertebrae in 5 cases, not contacting the upper and lower endplates at the same time) according to whether bone cement contacted the upper and lower endplates at the same time. Patients in the bilateral group were sub-divided into groups C(11 vertebrae in 11 cases, contacting the upper and lower endplates at the same time) and D(16 vertebrae in 16 cases, not contacting with the upper and lower endplates at the same time). Visual analogue scale score, Oswestry disability index, and Cobb angle were compared between unilateral and bilateral groups before and 1 year after surgery. The compression rate between adjacent vertebral bodies and the angle between the upper and lower endplates were compared between groups A, B, C and D. This study was approved by the Medical Ethics Committee of the Second Affiliated Hospital of Shanxi Medical

关 键 词：骨水泥分布 骨质疏松性椎体压缩骨折 椎体成形术 骨折 相邻椎体 骨质疏松 单侧穿刺 单节段 

分 类 号：R459.9[医药卫生—治疗学] R318.08[医药卫生—临床医学]