STEMI患者PCI术后ECG指标变化和心功能关系的研究  

Observation of ECG changes and cardiac function in patients with STEMI after PCI

作　　者：王娜[1] 邹宁[2] WANG Na;ZOU Ning(Department of Cardiology,the Second Hospital of Qinhuangdao,Qinhuangdao Hebei 100191,China;Department of Neurology, the Second Hospital of Qinhuangdao, Qinhuangdao Hebei 100191, China)

机构地区：[1]秦皇岛市第二医院心内二科,河北秦皇岛100191 [2]秦皇岛市第二医院神经内科,河北秦皇岛100191

出　　处：《新疆医科大学学报》2020年第4期454-457,共4页Journal of Xinjiang Medical University

基　　金：秦皇岛市科学技术研究与发展计划(201902A085)。

摘　　要：目的研究ST段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入治疗(PCI)术后心电图(ECG)指标和心功能的关系。方法2016年6月-2019年2月对在秦皇岛市第二医院进行治疗的118例STEMI患者进行前瞻性研究,入组患者均根据术前心电图进行心肌缺血分级,II级(A组),III级(B组),对两组患者心功能、心肌损伤标志物含量及心血管不良事件的发生情况进行分析。结果术后随访6个月,其中有8例失访。术后6个月,B组患者血清肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)和脑利钠肽(BNP)含量均高于A组,B组患者左室舒张末内径(LVEDd)高于A组,左心室射血分数(LVEF)低于A组,B组患者C反应蛋白(CRP)及肿瘤坏死因子-α(TNF-α)含量高于A组,B组心血管不良事件的发生率显著高于A组,差异均有统计学意义(P<0.05)。结论心电图心肌缺血分级与患者术后的心功能改善、心血管不良事件的发生存在密切关系,心电图对于STEMI患者的预后评估可能具有重要的指导价值。Objective To observe and study the relationship between ECG and cardiac function after PCI in patients with STEMI.MethodsThe data of 118 patients with STEMI treated in our hospital from June 2016 to February 2019 were prospectively studied.All the patients in the group were divided into two groups:grade II(group A)and grade III(group B)according to the myocardial ischemia grade.The cardiac function,the content of myocardial injury markers and the occurrence of cardiovascular adverse events in the two groups were observed and analyzed.ResultsThe follow-up period was 6 months,of which 8 cases were lost.Six months after the operation,the levels of serum cTnI,CK-MB and BNP in the group B were significantly higher than those in the control group,the LVEDd of group B was higher than that of group A,and the LVEF of group B was lower than that of group A.The levels of CRP and TNF-αin group B were significantly higher than those in group A.The incidence of adverse cardiovascular events in group B was significantly higher than that in group A.The statistical analysis showed that the difference was significant(P<0.05).ConclusionThe grade of myocardial ischemia in ECG is closely related to the improvement of cardiac function and the occurrence of adverse cardiovascular events after operation.ECG maybe has important guiding value for the prognosis evaluation of patients with STEMI.

关 键 词：ST段抬高型心肌梗死 PCI术 心电图 心功能 

分 类 号：R541[医药卫生—心血管疾病]