儿童和老年泛发性脓疱性银屑病临床特征分析  

Clinical characteristics and differences of generalized pustule psoriasis in children and the elderly

作　　者：李艺帆 史飞 郭杰 LI Yi-fan;SHI Fei;GUO Jie(The First Clinical School of Beijing University of Traditional Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学第一临床医学院,100029 [2]空军特色医学中心

出　　处：《实用皮肤病学杂志》2020年第1期12-15,共4页Journal of Practical Dermatology

摘　　要：目的探讨儿童和老年泛发性脓疱性银屑病(GPP)的临床特征及两者的差异。方法将53例GPP患者按照年龄分为儿童组(年龄≤14岁)和老年组(年龄≥60岁),对两组患者资料进行回顾性总结及分析。结果在诱发因素中儿童组感染占比高于老年组,药物及精神占比低于老年组;在临床特点方面,儿童组皮损初发部位在四肢、发热、指甲病变及白蛋白降低、高密度脂蛋白减低、红细胞沉降率加快的发生率低于老年组,而肌酐降低发生率高于老年组;儿童组多并发感染性疾病,老年组多并发代谢性疾病。结论儿童GPP最常见的诱因是感染,而老年是药物及精神因素;儿童与老年GPP的皮损表现各有特点;老年患者常并发其他系统疾病,更倾向于是一种系统性疾病,尤以代谢性疾病为常见。Objective To investigate the clinical characteristics and differences of generalized pustule psoriasis(GPP)in children and the elderly.Methods Fifty-five patients with GPP were divided into the children group(age≤14 years)and the elderly group(age>60 years)according to the patients’age.Then the data of the two groups were retrospectively summarized and analyzed.Results Among the inducing factors,the proportion of infection in the children group was higher than that in the elderly group,and the proportion of drug and spirit was lower than that in the elderly group.In terms of clinical characteristics,the incidence of skin lesions in the extremities,fever,nail lesions,decreased albumin,decreased high-density lipoprotein and accelerated erythrocyte sedimentation rate in the children group was lower than that in the elderly group,while the incidence of reduced creatinine was higher than that in the elderly group.Besides,infectious diseases were more common in children,while metabolic diseases were more common in the elderly.Conclusion Infection is the most common cause of GPP in children,while the most common cause of GPP in the elderly is drug and psychiatric factors.The skin lesions of GPP in children and the elderly have different characteristics.The elderly patients often suffer from some systemic diseases,which tend to be systemic,especially metabolic diseases.

关 键 词：银屑病 脓疱性 泛发性 儿童 老年 临床特征 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]