水貂病毒性肠炎和水貂犬瘟热研究进展  

Process in Mink Viral Enteritis and Mink Distemper

作　　者：朱翔宇 蔡熙姮 白雪[1,2] 闫喜军 胡博 Zhu Xiangyu;Cai Xiheng;Bai Xue;Yan Xijun;Hu Bo(Institue of Special Wild Economic Animal and Plant Science,Chinese Academy of Agricultural Science,Changchun 130112,China;Key Laboratory of Special Animal Epidemic Disease,Changchun 130112,China)

机构地区：[1]中国农业科学院特产研究所,长春130112 [2]农业农村部经济动物疫病重点实验室,长春130112

出　　处：《畜牧兽医科学（电子版）》2020年第6期1-6,16,共7页Graziery Veterinary Sciences：Electronic Version

基　　金：国家重点研发计划项目(2017YFD0501600)。

摘　　要：水貂细小病毒(Mink enteritis virus,MEV)和水貂犬瘟热病毒(Canine distemper virus)是威胁水貂健康的常见病原,分别引起水貂病毒性肠炎和水貂犬瘟热2种传染病,这2种传染病都是急性、高度接触性传染病,虽然接种合格的疫苗是有效的防控手段,但是病毒基因的变异、跨物种间传播、跨地区地域传播以及不同地域病毒之间出现的重组等因素,都可导致免疫失败,病毒一旦在群体间流行并传播,动物感染后仍会出现极高的发病率和死亡率。水貂细小病毒和水貂犬瘟热病毒给毛皮动物养殖业以及野生珍稀动物的保护带来的影响和危害,应适当予以重视。该文综述MEV和CDV的病原学和致病机理、流行病学和分子生物学、实验室诊断方法以及疫苗研究。Mink enteritis virus(MEV)and mink canine distemper virus(CDV)are common pathogens that threaten the health of mink,causing mink viral enteritis and mink canine distemper respectively.Both infectious diseases are acute,high-contact infectious diseases.Although qualified vaccination is an effective means of prevention and control,the continuous mutation of virus genes,inter-species transmission,cross-regional transmission,and mutual recombination of viruses from different regions are the main reasons for the failure of immunity.Once the virus has spread and spread among populations,animal infections will still have extremely high morbidity and mortality.The impact and harm of mink parvovirus and mink canine distemper virus on fur animal breeding and the protection of wild and rare animals,due attention should be paid to it.This article reviews the etiology,molecular biology and epidemiology,pathogenesis,laboratory diagnostic methods,and vaccine research of MEV and CDV.

关 键 词：水貂病毒性肠炎 水貂犬瘟热 致病机理 检测方法 免疫预防 

分 类 号：S865.2[农业科学—野生动物驯养]