珠海市首起新型冠状病毒肺炎聚集性疫情流行病学调查  

A survey on the first clustering of coronavirus disease 2019 in Zhuhai city

作　　者：萧松建[1] 周奕[2] 张雪宝[1] 林新天[1] 陈龙[1] 倪锡河[1] 黄思成 阮峰[1] XIAO Song-jian;ZHOU Yi;ZHANG Xue-bao(Office of Health Emergency Response,Zhuhai Municipal Center for Disease Control and Prevention,Zhuhai,Guangdong Province 519000,China;不详)

机构地区：[1]珠海市疾病预防控制中心应急办,珠海519000 [2]中山大学附属第五医院

出　　处：《中国公共卫生》2020年第3期273-276,共4页Chinese Journal of Public Health

摘　　要：目的分析广东省珠海市首起新型冠状病毒肺炎(COVID-19)聚集性疫情的流行病学特征、感染来源和传播方式。方法2020年1月20日广东省珠海市报告3例COVID-19确诊病例,及其50名密切接触者。采用现场流行病学方法追踪调查,RT-PCR方法检测新型冠状病毒(SARS-CoV-2)核酸。结果2例病例为武汉的一对夫妻,1月7日在武汉聚会时感染SARS-CoV-2,1月11日到珠海后传染给女儿。夫妻2人发病潜伏期为5 d,均为危重症病例,其中病例1死亡;其女儿病例3发病潜伏期<6 d,为普通型病例。病例1鼻咽拭子和肛拭子病毒核酸阳性持续31 d,病例2危重症病例核酸阳性持续18 d,病例3普通型病例核酸阳性持续5 d。共搜索到密切接触者50人,经14 d医学观察均无异常,核酸检测均为阴性。结论本事件为一起COVID-19聚集性疫情,证实SARS-CoV-2人传人的传播模式,主要通过飞沫或接触传播,气溶胶传播的可能性较小。Objective To analyze epidemiological characteristics,infection source and transmission route of the first clustering of coronavirus disease 2019(COVID-19)in Zhuhai city of Guangdong province.Methods We carried out a field survey on 3 laboratory-confirmed cases of COVID-19 in a family and 50 close contacts of the cases on January 20,2020 in the city.Results The first two cases of the clustering were a couple(the man aged 78 years and the women 76 years)and they had a history of a 5-day traveling in Wuhan city and having a dinner with family members in the city;the two cases had severe symptoms and were admitted into hospitals on January 17,2020 and were confirmed positive for novel conronavirus nucleic acid the next day.The estimated incubation period was 5 days for the two cases.The third case of the clustering was the couple's daughter(49 years)with mild symptoms and laboratory confirmation;the third case had histories of a 7-day living together with and taking hospitalization care of the first two cases;the estimated incubation period for the case was less than 6 days.The duration was 30-day and 18-day for the first and second case's throat and anal swab specimens positive to viral nucleic acid but 5-day for the third case's throat swab specimens,respectively.No specimens of novel conronavirus nucleic acid positive were detected during the 14 day's medical observation among the 50 close contacts of the three cases.Conclusion The survey confirms a clustering of COVID-19 and human-to-human transmission the novel coronavirus.

关 键 词：新型冠状病毒 聚集性疫情 流行病学 调查 

分 类 号：R181.81[医药卫生—流行病学] R373.1[医药卫生—公共卫生与预防医学]