持续加温湿化与持续滴注湿化液气道湿化对气管切开非机械通气患者影响的Meta分析  

Effects of continuous warm humidification and continuous instillation with humidified fluid for airway humidification in patients undergoing tracheotomy and non-mechanical ventilation:a Meta-analysis

作　　者：肖力 温贤秀[2] 张娟 邓小春[1,2] 周开敏 Xiao Li;Wen Xianxiu;Zhang Juan;Deng Xiaochun;Zhou Kaimin(School of Nursing,Chengdu University of TCM,Chengdu 610000,Sichuan,China;Sichuan Academy of Medical Sciences·Sichuan Provincial People’s Hospital,Chengdu 610072,Sichuan,China;Department of Nursing,The Fourth People’s Hospital of Chengdu,Chengdu 610000,Sichuan,China)

机构地区：[1]成都中医药大学护理学院,四川成都610000 [2]四川省医学科学院·四川省人民医院,四川成都610072 [3]四川省成都市第四人民医院护理部,四川成都610000

出　　处：《右江民族医学院学报》2020年第2期197-203,共7页Journal of Youjiang Medical University for Nationalities

基　　金：2016年四川省卫生和计划生育委员会科研课题(普及应用项目)立项课题(16PJ494)。

摘　　要：目的评价持续加温气道湿化和微量泵持续滴注湿化液气道湿化对气管切开非机械通气患者的影响。方法检索PubMed、EMBASE、JBI循证护理中心图书馆、the Cochrane Library、中国知网、万方数据库、维普数据库、中国生物医学文献数据库中相关随机对照试验(RCT)文献后,采用RevMan 5.2软件进行Meta分析。结果共纳入9篇RCT,包含497例研究对象。与微量泵持续滴注湿化液气道湿化相比,持续加温气道湿化可降低气管切开非机械通气患者的刺激性咳嗽率(P<0.00001)、气道黏膜出血率(P<0.0001)、肺部感染发生率(P<0.0001)、痰痂形成率(P<0.00001),同时可提高患者湿化效果满意率(P=0.001)。结论持续加温气道湿化法的气道湿化效果优于持续滴注湿化液气道湿化法。Objective To evaluate the effects of continuous warm airway humidification and continuous instillation with humidified fluid by micro bump for airway humidification in patients with tracheotomy and non-mechanical ventilation.Methods Literatures on related randomized controlled trials(RCTs)were retrieved on PubMed,EMBASE,JBI evidence-based nursing center library,the Cochrane Library,China National Knowledge Internet(CNKI),Wanfang Chinese databases,VIP and China Biology Medicine disc(CBM).Then RevMan 5.2 Software was used for Meta-analysis.Results Nine RCTs were included altogether,including 497 participants.Compared with continuous instillation with humidified fluid by micro bump for airway humidification,continuous warm airway humidification could reduce the incidences of irritable cough(P<0.00001),the rate of airway mucosal hemorrhage(P<0.0001),the incidence of lung infection(P<0.0001)and the formation rate of sputum scab(P<0.00001),and at the same time increase the rate of patients’satisfaction with humidification(P=0.001)in patients undergoing tracheotomy and non-mechanical ventilation.Conclusion Continuous warm airway humidification has better effect on airway humidification than continuous instillation with humidified fluid for airway humidification.

关 键 词：气管切开术 气道湿化 非机械通气 系统综述 META分析 

分 类 号：R653[医药卫生—外科学]