白塞病相关致病因素研究进展  

Progress of environmental and psychological factors in the pathogenesis of Behcet’s disease

作　　者：陈瑜佳 管剑龙[1] CHEN Yu-jia;GUAN Jian-long(Department of Rheumatology and Immunology, Huadong Hospital, Fudan University, Shanghai 200040, China)

机构地区：[1]复旦大学附属华东医院风湿免疫科,上海200040

出　　处：《中国临床医学》2020年第2期327-330,共4页Chinese Journal of Clinical Medicine

基　　金：上海申康医院发展中心临床科技创新项目(SHDC12017129).

摘　　要：白塞病(Behcet’s disease,BD)是一种病因未明的系统性血管炎,流行于丝绸之路沿线,又称“丝绸之路病”。其确切发病机制仍未阐明,目前研究多支持其发生与遗传、免疫、环境等因素有关。地理环境、微生物、吸烟和心理精神因素等对BD发病也有一定影响。本文主要对可能导致BD发病的上述因素作一综述。Behcet’s disease(BD),also called“Silk Route Disease”due to its predominant prevalence through the Silk Road,is a kind of systemic vasculitis.Genetic,immune and enviromental factors are thought to contribute to its pathogenesis,although the precise mechanism remains unclear.Geographical environment,smoking,microorganism and psychological factors are involved in the occurrence of BD.In this review,we outline the roles of the above factors in BD.

关 键 词：白塞病 致病因素 地理环境 微生物 吸烟 心理 

分 类 号：R543[医药卫生—心血管疾病]