急性心肌梗死患者多支冠脉病变的危险因素分析  

Risk Factors of Multiple Coronary Artery Disease in Patients with Acute Myocardial Infarction

作　　者：刘佳 楚英杰 LIU Jia;CHU Ying-jie(Department of Cardiology,Zhengzhou University people’s Hospital,Henan Provincial People’s Hospital,Zhengzhou 450003,China)

机构地区：[1]郑州大学人民医院/河南省人民医院心内科,河南郑州450003

出　　处：《河南医学研究》2020年第11期1951-1953,共3页Henan Medical Research

基　　金：河南省重点科技攻关计划项目(122102310068)。

摘　　要：目的将急性心肌梗死(AMI)患者分为单支病变组和多支病变组,对比分析两组差异,探索AMI患者多支冠脉病变的危险因素。方法选取2017年10月至2018年5月就诊于郑州大学人民医院并接受CT冠脉造影(CAG)检查的122例AMI患者,分为单支病变组(25例)和多支病变组(97例)。对比两组资料,利用回归分析探索多支冠脉病变的危险因素。结果多支病变组患者年龄[(59.64±11.99)岁]高于单支病变组[(53.36±11.18)岁],血清载脂蛋白B100(ApoB100)水平[(0.90±0.21)g·L-1]高于单支病变组[(0.80±0.20)g·L-1],差异有统计学意义(均P<0.05)。Logistic回归分析示高龄和血清ApoB100水平增高为AMI患者多支冠脉病变的危险因素。结论高龄和血清ApoB100水平升高是AMI患者多支冠脉病变的危险因素。Objective To divide the patients with acute myocardial infarction(AMI)into single-vessel disease group and multi-vessel disease group,and analyze the differences between the 2 groups to explore the risk factors of multiple coronary artery disease in AMI patients.Methods A total of 122 AMI patients who underwent CT coronary angiography(CAG)examination at Zhengzhou University People’s Hospital from October 2017 to May 2018 were divided into single-vessel disease group(25 cases)and multiple-vessel disease group(97 cases).The data of the 2 groups were compared,and the risk factors of multiple coronary artery disease were explored by regression analysis.Results In multiple-vessel disease group,age of patients[(59.64±11.99)years]was higher than that in single-vessel disease group[(53.36±11.18)years],serum apolipoprotein B100(ApoB100)level[(0.90±0.21)g·L-1]was higher than that in single-vessel disease group[(0.80±0.20)g·L-1],and the differences were statistically significant(both P<0.05).Logistic regression showed that agedness and elevated serum ApoB100 level were risk factors for multiple coronary artery disease in AMI patients.Conclusion Agedness and elevated serum ApoB100 level were risk factors for multiple coronary artery disease in AMI patients.

关 键 词：冠心病 急性心肌梗死 年龄 载脂蛋白B100 

分 类 号：R541.4[医药卫生—心血管疾病]