烟酸生产过程中硫酸盐含量的快速测定  

Determination of Sulfate content in Nicotinic Acid Production Process

作　　者：肖棱 尹春林 颜欣 王素彬 谢海容 左珍燕 Xiao Ling;Yin Chun-lin;Yan Xin;Wang Su-bin;Xie Hai-rong;Zuo Zhen-yan(Sichuan Yinhe Chemical Co.,Ltd.Mianyang,Mianyang,Sichuan 622650,China.;Mianyang Weida Pharmaceutical Technology Co.,Ltd.Mianyang,Sichuan 622650,China;Sichuan Jingbiao testing Technology Co.,Ltd.Mianyang,Sichuan 622650,China)

机构地区：[1]四川省银河化学股份有限公司,四川绵阳622650 [2]绵阳市崴尼达医药科技有限责任公司,四川绵阳622650 [3]四川精标检测技术有限公司,四川绵阳622650

出　　处：《福建分析测试》2020年第2期30-33,共4页Fujian Analysis & Testing

摘　　要：本文建立一种快速测定烟酸生产过程中烟酸料液硫酸盐含量的方法。在试样中加入钍试剂,再用0.01 mol/L氯化钡标准溶液滴定试样,直至溶液颜色变为砖红色即为终点,整个过程只需5 min。用重量法验证,结果表明此方法测定的结果与重量法测定的结果无显著性差异。此方法可快速、准确测定烟酸生产过程中不同阶段烟酸中硫酸盐的含量,为烟酸的质量和生产成本提供了科学依据。a method for the rapid determination of sulfate content of fumaric acid in the process of niacin production was es?tablished.In the sample,a thorium reagent is added,and the sample is titrated with a standard solution of 0.01 mol/L chlo?ride until the solution color becomes brick red,which is the end point.The entire process requires only 5 min.The results show that there is no significant difference between the method.This method can be used to determine the sulfate content of niacin at different stages of niacin production,which provides scientific basis for niacin quality and production cost.

关 键 词：硫酸盐 钍试剂 钡离子 烟酸 化学滴定 

分 类 号：X83[环境科学与工程—环境工程]