A novel double polymer modified hydrophobic/hydrophilic stationary phase for liquid chromatography  

作　　者：Fangbin Fan Jingjun Pan Yijing Li Licheng Wang Shuai Wang Xiaojing Liang Yong Guo 

机构地区：[1]Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province,Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000,China [2]University of Chinese Academy of Sciences,Beijing 100049,China [3]Engineering Technology Institute of Xinjiang Oilfield Company,Kelamayi 834000,China

出　　处：《Chinese Chemical Letters》2020年第3期746-750,共5页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.21575148,21575149,21505146)。

摘　　要：In this paper,norbornene imidazolium hexafluorophosphate(NM-MIm-PF6)was modified on the surface of aminopropyl silica by ring-opening metathesis polymerization(ROMP),and then oligo(ethylene glycol)methacrylate(OEGMA)were grafted on the surface by atom transfer radical polymerization(ATRP).Some characterizations in this article confirmed that the synthesis of P(NM-MIm-PF6)-SiPOEGMA(Pl-Si-P2)is successful.The P1-Si-P2 can separate sugars,amino acids,sulfonamides in a hydrophilic interaction mode and alkyl benzene,polycyclic aromatic hydrocarbon in a reverse phase mode.The experiment also found that the column has typical characte ristics of hydrophobic/hydrophilic separation mechanism.Compared to single hydrophobic C18 column and single hydrophilic Si-NH2 column,this P1-Si-P2 shows certain advantages.

关 键 词：NORBORNENE IMIDAZOLIUM hexafluorophosphate(NM-MIm-PF6) Oligo(ethylene glycol)methacrylate(OEGMA) HYDROPHOBIC HYDROPHILIC Liquid chromatography(LC) 

分 类 号：O652.63[理学—分析化学]