All-small-molecule dynamic covalent gels with antibacterial activity by boronate-tannic acid gelation  

作　　者：Xuejing Cheng Mengyu Li Hui Wang Yiyun Cheng 

机构地区：[1]Shanghai Key Laboratory of Regulatory Biology,School of Life Sciences,East China Normal University,Shanghai 200241,China [2]South China Advanced Institute for Soft Matter Science and Technology,South China University of Technology,Guangzhou 510640,China

出　　处：《Chinese Chemical Letters》2020年第3期869-874,共6页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.21725402);the Shanghai Municipal Science and Technology Commission(No.17XD1401600)。

摘　　要：Reversible boronate-catechol linkage was widely used to construct two-dimensional coatings and threedimensional nanostructures or hydrogels.The construction of these functional materials usually requires the pre-synthesis of macro molecular building blocks,and direct gelation between natural polyphenols and small molecule boranic acids is yet to be investigated.In this study,we fabricated a family of allsmall-molecule dynamic covalent gels consisting of tannic acid and boronic acids.Transparent and thixotropic gels were formed by boronate affinity towards catechol groups abundant on natural polyphenols.The gels showed multi-responsiveness,such as acid-,base-,reduction-and oxidantsensitive depending on the used boronic acid building blocks.The chemistry for gel formation and stimuli-responsiveness was characterized by11B NMR spectroscopy.The multi-stimuli responsiveness,green processing and facile modular design make the boronic acid-tannic acid gels promising candidates for the development of smart soft materials.

关 键 词：Nature polyphenols Boronic acids Hydrogels Boronate-catechol complexation All-small-molecule DYNAMIC COVALENT GELS 

分 类 号：TQ427.26[化学工程]