阿托伐他汀联合阿司匹林治疗冠心病的临床效果  

Clinical effect of Atorvastatin combined with Aspirin in the treatment of coronary heart disease

作　　者：王琦[1] WANG Qi(Department of Cardiovascula Medicine,Nanhai District People′s Hospital of Foshan City,Guangdong Province,Foshan520200,China)

机构地区：[1]广东省佛山市南海区人民医院心血管内科,广东佛山520200

出　　处：《中国当代医药》2020年第10期43-45,共3页China Modern Medicine

摘　　要：目的探讨阿托伐他汀联合阿司匹林治疗冠心病的效果。方法选取2018年1月~2019年1月我院收治的110例冠心病患者作为研究对象,按照平均分类法分为对照组与观察组,每组各55例。对照组患者采用阿司匹林治疗,观察组患者采用阿托伐他汀联合阿司匹林治疗。比较两组患者的治疗效果、血脂水平、心绞痛发作持续时间以及不良反应。结果观察组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组患者治疗后的三酰甘油、血清总胆固醇、低密度脂蛋白胆固醇均低于对照组,差异有统计学意义(P<0.05);观察组患者治疗后的高密度脂蛋白胆固醇高于对照组,差异有统计学意义(P<0.05);观察组患者治疗后的心绞痛发作持续时间短于对照组,差异有统计学意义(P<0.05);两组患者的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论采用阿托伐他汀联合阿司匹林治疗冠心病,能够提高冠心病患者的临床效果,值得推广应用。Objective To discuss the effect of Atorvastatin combined with Aspirin in the treatment of coronary heart disease. Methods A total of 110 patients with coronary heart disease treated in our hospital from January 2018 to January 2019 were selected as the study subjects. According to the average classification method, they were divided into the control group and the observation group, with 55 cases in each group. The control group was treated with Aspirin.The observation group was treated with Atorvastatin in combination with Aspirin. The treatment effect, blood lipid levels, duration of angina pectoris, and adverse reactions were compared between the two groups. Results The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant(P<0.05). The levels of triglyceride, serum total cholesterol and low-density lipoprotein cholesterol in the observation group were lower than those in the control group, the differences were statistically significant(P<0.05). The highdensity lipoprotein cholesterol of the observation group was higher than that of the control group after treatment, and the difference was statistically significant(P<0.05). The duration of angina pectoris in the observation group was shorter than that in the control group, and the difference was statistically significant(P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05). Conclusion Atorvastatin combined with Aspirin in the treatment of coronary heart disease can improve the clinical effect of patients with coronary heart disease, which is worthy of popularization and application.

关 键 词：阿托伐他汀 阿司匹林 联合使用 冠心病 临床效果 

分 类 号：R743.3[医药卫生—神经病学与精神病学]