小儿复方氨基酸注射液联合消旋卡多曲颗粒治疗轮状病毒肠炎患儿的临床效果  

Clinical effect of Pediatric Compound Amino Acid Injection combined with Racecadotril Granules on children with rotavirus enteritis

作　　者：吴元芳[1] 黄惠仪 余淑娟 WU Yuan-fang;HUANG Hui-yi;YU Shu-juan(Department of Pediatrics,Kaiping Central Hospital,Guangdong Province,Kaiping529300,China)

机构地区：[1]广东省开平市中心医院儿科,广东开平529300

出　　处：《中国当代医药》2020年第10期133-135,共3页China Modern Medicine

摘　　要：目的研究小儿复方氨基酸注射液(18AA-Ⅱ)联合消旋卡多曲颗粒治疗轮状病毒肠炎患儿的临床效果。方法选取2017年3月~2018年1月我院收治的150例轮状病毒肠炎患儿为研究对象,按随机数字表法将其分为试验组(n=75)和对照组(n=75)。对照组采用常规抗炎抗病毒补液治疗,试验组在对照组的基础上采用18AA-Ⅱ联合消旋卡多曲颗粒治疗。比较两组的临床治疗效果、临床症状改善时间及不同时间血清C反应蛋白(CRP)水平。结果治疗后,试验组临床总有效率为90.67%,高于对照组的76.00%,差异有统计学意义(P<0.05);试验组纠正脱水时间、止泻时间、退热时间和止吐时间短于对照组,差异均有统计学意义(P<0.05);试验组治疗后24、48、72 h CRP水平低于对照组,差异有统计学意义(P<0.05)。结论 18AA-Ⅱ联合消旋卡多曲颗粒治疗轮状病毒肠炎患儿的临床效果好,可缩短患儿症状缓解时间,增强抗炎效果。Objective To study the clinical effect of Pediatric Compound Amino Acid Injection(18 AA-Ⅱ) combined with Racecadotril Granules on children with rotavirus enteritis. Methods A total of 150 children with rotavirus enteritis treated in our hospital from March 2017 to January 2018 were selected as study subjects. They were divided into test group(n=75) and control group(n=75) by random number table method. The children in the control group were treated with conventional anti-inflammatory and antiviral and fluid replacement. The test group was treated with 18 AA-Ⅱ with Racecadotril Granules on the basis of conventional treatment. The clinical effect, clinical symptom improvement time and serum C-reactive protein(CRP) levels at different periods of the two groups were compared. Results After treatment, the total clinical effective rate of patients in the test group was 90.67%, higher than that of the control group accounting for 76.00%, the difference was statistically significant(P<0.05). The corrected dehydration time, antidiarrheal time, antipyretic time and vomiting stopping time in the test group were shorter than those in the control group, the differences were statistically significant(P<0.05). CRP levels of the children in the test group at 24, 48, and 72 h after treatments were lower than those in the control group, the difference was statistically significant(P<0.05). Conclusion The 18 AA-Ⅱcombined with Racecadotril Granules in children with rotavirus enteritis has a good clinical effect, which can effectively shorten the symptom relief time and enhance the anti-inflammatory effect.

关 键 词：小儿氨基酸 消旋卡多曲 轮状病毒 C反应蛋白 

分 类 号：R725.1[医药卫生—儿科]