哺乳动物DGAT基因与泌乳性状关联性研究进展  

Advances on the Relationship between Mammalian DGAT Gene and Lactation Traits

作　　者：姚怀兵 李玲 马强 阿尔曼·海热 苗静 陈钢粮 唐钊 杨洁[1] YAO Huaibing;LI Ling;MA Qiang;Aerman·Haire;MIAO Jing;CHEN Gangliang;TANG Zhao;YANG Jie(College of Life Science and Technology,Xinjiang University,Urumqi,Xinjiang 830046,China;College of Animal Science,Xinjiang Agricultural University,Urumqi,Xinjiang 830052,China;Xinjiang Wangyuan Biological Science and Technology Group Co.Ltd.,Altay,Xinjiang 836500,China)

机构地区：[1]新疆大学生命科学与技术学院,新疆乌鲁木齐830046 [2]新疆农业大学动物科学学院,新疆乌鲁木齐830052 [3]新疆旺源生物科技集团有限公司,新疆阿勒泰836500

出　　处：《家畜生态学报》2020年第4期1-7,共7页Journal of Domestic Animal Ecology

基　　金：新疆维吾尔自治区重点研发专项(201804081);国家自然科学基金(31471645)。

摘　　要：泌乳是哺乳动物重要性状之一,尤其是在乳用家畜上,能直接影响畜牧业的经济效益。哺乳动物体内二酰基甘油酰基转移酶(DGAT)是控制甘油三酯合成的关键微粒体酶,主要有DGAT1、DGAT2两个亚型。已有诸多研究表明DGAT基因与动物脂肪沉积、产奶性能、泌乳品质等性状密切相关。文章主要简述哺乳动物体内DGAT基因的发现、定位、结构、生物学效应及遗传多态性与泌乳性状的关联性,旨在为哺乳动物泌乳性状相关的分子标记筛选及生产实践提供参考和理论依据。Lactation is one of the important economic traits of mammals,especially in dairy livestock,which can directly affect the economic benefits of animal husbandry.Diacylglycerol acyltransferase(DGAT)is a crucial microsomal enzyme for controlling triglyceride synthesis in mammals.It is mainly composed of two subtypes,DGAT1 and DGAT2.Many researches have proved that DGAT genes are closely related to animal fat deposition,milk production performance,lactation quality and other traits.This review summarized the relationship between the discovery,location,structure,biological effects and genetic polymorphisms and milk production traits of mammalian DGAT genes,aiming to provide reference and theoretical basis for molecular markers'screening and production practice.

关 键 词：哺乳动物 DGAT1基因 DGAT2基因 泌乳性状 关联性研究 

分 类 号：S811.5[农业科学—畜牧学]