卡前列素氨丁三醇预防妊娠期高血压的效果及出血情况分析  

Effect of Carprost Aminobutanediol in Preventing Hypertension during Pregnancy and Its Bleeding Were Analyzed

作　　者：李享 LI Xiang(Department of Obstetrics and Gynecology,Tieling Women's and Children's Hospital,Tieling 112000,China)

机构地区：[1]铁岭市妇婴医院妇产科,辽宁铁岭112000

出　　处：《中国医药指南》2020年第11期128-129,共2页Guide of China Medicine

摘　　要：目的分析卡前列素氨丁三醇预防妊娠期高血压产后出血的临床疗效及出血情况。方法选取2017年2月至2018年8月来我院妇产科分娩的93例妊娠期高血压孕产妇为研究组,另选择同期93例正常孕产妇为对照组。研究组产妇在胎儿娩出后给予卡前列素氨丁三醇治疗,对照组产妇在胎儿娩出后给予宫缩素治疗,比较两组患者的产中及产后2 h,24 h的出血量、出血量分布情况及不良反应发生情况。结果研究组产妇产中,产后2 h及24 h出血量分别为(112.55±30.44)mL,(139.07±41.16)mL,(238.36±51.92)mL,均明显低于对照组的(152.93±32.05)mL,(187.23±60.93)mL,(352.87±77.36)mL,两组差异比较有统计学意义(P<0.05);研究组的出血率为6.45%,对照组的出血率为18.28%,研究组显著低于对照组,两组比较具有统计学意义(P<0.05)。结论卡前列素氨丁三醇能够有效预防妊娠期高血压产后出血,对改善母婴结局有重大意义,值得在临床大力推广。Objective To analyze the clinical effi cacy and bleeding status of carprost aminoglycol in preventing postpartum hemorrhage from pregnancy hypertension.Methods From February 2017 to August 2018,93 pregnant women with gestational hypertension who gave birth in the department of obstetrics and gynecology of our hospital were selected as the study group,and 93 normal pregnant women in the same period were selected as the control group.The puerpera of the study group was given carprost aminobutanol treatment after delivery of the fetus,and the puerpera of the control group was given oxytocin treatment after delivery of the fetus,and the bleeding volume,bleeding volume distribution and adverse reactions of the two groups of patients were compared in the delivery and 2 h after delivery,24 h after delivery.Results In the study group,the blood loss at 2 h and 24 h after delivery was(112.55±30.44)mL,(139.07±41.16)mL,(238.36±51.92)mL,which was signifi cantly lower than the control group(152.93±32.05)mL,(187.23±60.93)mL,(352.87±77.36)mL,the difference between the two groups was statistically significant(P<0.05).The bleeding rate of the study group was 6.45%,and that of the control group was 18.28%.The bleeding rate of the study group was signifi cantly lower than that of the control group,and the comparison between the two groups was statistically significant(P<0.05).Conclusion Carprost aminobutanediol can effectively prevent postpartum hemorrhage from hypertension during pregnancy,which is of great signifi cance for improving maternal and infant outcomes and is worthy of clinical promotion.

关 键 词：卡前列素氨丁三醇 妊娠期高血压 宫缩素 产后出血 

分 类 号：R714.252[医药卫生—妇产科学] R714.461[医药卫生—临床医学]