血液检验在儿童贫血诊断与鉴别诊断中的价值分析  

Value of Blood Test in Diagnosis and Differential Diagnosis of Anemia in Children

作　　者：张芳 ZHANG Fang(Department of Laboratory,Donggang Maternal and Child Health Family Planning Service Center,Donggang 118300,China)

机构地区：[1]东港市妇幼保健计划生育服务中心检验科,辽宁东港118300

出　　处：《中国医药指南》2020年第12期179-180,共2页Guide of China Medicine

摘　　要：目的分析血液检验在儿童贫血诊断与鉴别诊断中的价值。方法选择我院于2017年12月至2018年12月收治的50例地中海贫血患儿与50例缺铁性贫血患儿作为研究对象,以同时期在我院接受健康体检的50例儿童作为健康对照组,所有儿童均于清晨空腹时采用EDTA-K3真空抗凝管抽取2 mL静脉血,混匀后于2 h内采用全自动血液分析仪检测红细胞计数(RBC)、红细胞平均血红蛋白(MCH)、血红蛋白(Hb)、红细胞体积分布宽度(RDW)、血红蛋白平均浓度(MCHC)、红细胞平均体积(MCV)。比较三组受检儿童的RBC、MCH、MCHC、Hb、RDW、MCV。结果IDA组RBC、MCH、MCHC显著低于THAL组与对照组(P<0.05);IDA组Hb、MCV显著高于THAL组(P<0.05),低于对照组(P<0.05);IDA组RDW显著高于THAL组与对照组(P<0.05);THAL组RBC、RDW显著高于对照组(P<0.05);THAL组MCH、MCHC、Hb、MCV显著低于对照组(P<0.05)。结论血液检验各指标在地中海贫血与缺铁性贫血中有不同程度的异常,可作为诊断与鉴别诊断儿童贫血的重要指标。Objective To analyze the value of blood test in the diagnosis and differential diagnosis of anemia in children.Methods 50 children with thalassemia and 50 children with iron deficiency anemia admitted to our hospital from December 2017 to December 2018 were selected as the research objects.50 children who underwent health examination at the same time were taken as the healthy control group.All children were taken 2 mL venous blood by EDTA-K3 vacuum anticoagulant tube in the morning fasting.After mixing,the red blood was detected by automatic blood analyzer within 2 hours.Cell count(RBC),mean hemoglobin(MCH),hemoglobin(Hb),red blood cell volume distribution width(RDW),mean hemoglobin concentration(MCHC),mean red blood cell volume(MCV),and the ratio of RBC to MCV were calculated.RBC,MCH,MCHC,Hb,RDW,MCV were compared among the three groups.Results RBC,MCH,MCHC,in IDA group were significantly lower than those in THAL group and control group(P<0.05);Hb and MCV in IDA group were significantly higher than those in THAL group(P<0.05),lower than those in control group(P<0.05);RDW in IDA group was significantly higher than those in THAL group and control group(P<0.05);RBC,RDW,in THAL group were significantly higher than those in control group(P<0.05);MCH,MCHC,Hb and MCV in THAL group were significantly lower than those in control group(P<0.05).Conclusion The blood test indicators are abnormal in different degrees in Mediterranean anemia and iron deficiency anemia,which can be used as an important index for the diagnosis and differential diagnosis of childhood anemia.

关 键 词：血液检验 儿童贫血 鉴别诊断 诊断价值 

分 类 号：R446.11[医药卫生—诊断学] R556[医药卫生—临床医学]