固肾安胎丸联合人绒毛膜促性腺激素治疗复发性流产临床效果  

Clinical effect of Gushen antai pill combined with human chorionic gonadotropin for treating women with recurrent spontaneous abortion

作　　者：芦艳丽[1] 万莉[1] 刘娜[1] 王新梅[1] 龚巍[1] LU Yanli;WAN Li;LIU Na;WANG Xinmei;GONG Wei(Affiliated Chinese Medicine Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830000)

机构地区：[1]新疆医科大学附属中医医院,乌鲁木齐830000

出　　处：《中国计划生育学杂志》2020年第3期335-337,共3页Chinese Journal of Family Planning

摘　　要：目的:了解固肾安胎丸联合人绒毛膜促性腺激素(HCG)治疗复发性流产(RSA)的临床效果。方法:选择88例复发性流产患者,依据治疗方式的不同分为对照组及观察组各44例。对照组予以HCG治疗,观察组予以HCG+固肾安胎丸联合治疗,观察两组治疗后的临床疗效,分析性激素及相关血清因子水平变化,观察不良反应。结果:治疗后,观察组临床总有效率(88.6%)高于对照组(65.9%)(P<0.05);两组孕酮(P)、雌二醇(E2)及HCG水平均较治疗前增加,且观察组高于对照组(均P<0.05);两组干扰素(INFγ)、血管内皮生长因子(VEGF)、同型半胱氨酸(HCY)水平均较治疗前降低,且观察组低于对照组(P<0.05)。结论:固肾安胎丸联合HCG可明显提高RSA患者临床疗效,其改善原因可能与有效调节患者性激素水平及相关血清因子水平有关。Objective:To explore the clinical effect of Gushen antai pill combined with human chorionic gonadotropin(HCG)for treating women with recurrent spontaneous abortion(RSA).Methods:88 women with RSA were selected as the study subjects and were divided into control group and observation group according to different treatment methods(44 cases in each group).The women in the control group were treated with HCG,while the women in the observation group were treated with HCG combined with Gushen antai pill.The clinical efficacy,the levels of sex hormones,and related serum factors before and after treatment of women in the two groups were observed.Results:After treatment,the total clinical effective rate of the women in the observation group was 88.6%,which was significant higher than that(65.9%)of women in the control group(P<0.05).The levels of P,E2 and HCG of women in the two groups were significant higher than those of women before treatment(P<0.05),and the levels of P,E2 and HCG of women in the observation group were significantly higher than those of women in the control group(P<0.05).The levels of INFγ,VEGF and HCY of women in the two groups were significant lower than those of women before treatment(P<0.05),and the levels of INFγ,VEGF and HCY of women in the observation group were significant lower than those in the control group(P<0.05).Conclusion:Gushen antai pill combined with HCG for treating women with RSA can significantly improve the clinical efficacy,which may be related to the regulation of sex hormone levels and related serum indicators.

关 键 词：复发性流产 固肾安胎丸 人绒毛膜促性腺激素 性激素 血清因子 

分 类 号：R71[医药卫生—妇产科学]