基于太赫兹量子级联激光器的生物医学成像研究进展  

Progress in Biomedical Imaging Based on Terahertz Quantum Cascade Lasers

作　　者：符张龙 李锐志 李弘义 邵棣祥 曹俊诚[1] Fu Zhanglong;Li Ruizhi;Li Hongyi;Shao Dixiang;Cao Juncheng(Key Laboratory of Terahertz Solid-State Technology,Shanghai Institute of Microsystem and Information Technology,Chinese Academy of Sciences,Shanghai 200050,China;University of Chinese Academy of Sciences,Beijing 100049,China)

机构地区：[1]中国科学院上海微系统与信息技术研究所太赫兹固态技术重点实验室,上海200050 [2]中国科学院大学,北京100049

出　　处：《中国激光》2020年第2期177-186,共10页Chinese Journal of Lasers

基　　金：国家重点研发计划(2017YFF0106302,2017YFA0701005,2018YFB1801502);国家自然科学基金(61927813,61975225,61875220,61775229,61704181);中国科学院基础前沿科学研究计划(ZDBS-LY-JSC009);上海市青年科技英才杨帆计划(17YF1429900)。

摘　　要：太赫兹(THz)波对生物医学组织具有天然的非电离性、水含量敏感性和浅层穿透性等特点,这使得其非常适合应用于生物医学成像。由于太赫兹量子级联激光器(THz QCL)具有激射功率高、光束质量好、调制速率高、体积小的特点,基于THz QCL的生物医学成像系统相较于其他主动式生物医学成像系统成像信噪比高、成像分辨率高、成像速度快、结构更紧凑。基于此,对基于THz QCL的生物医学成像研究进展进行综述,并对THz生物成像优势、THz QCL生物医学成像优势、生物医学成像系统、生物医学成像目标进行了总结,对其未来发展方向进行了展望。Terahertz(THz)waves are ideal for biomedical imaging because of its natural non-ionization properties,sensitivity to moisture,and penetration depth in biomedical tissues.The THz quantum cascade laser(QCL)has advantages of high power,good-quality spot,fast modulation rate,and tiny size.Compared with traditional biomedical imaging systems,the biomedical imaging systems based on THz QCL have a superior signal-to-noise ratio,higher imaging resolution,faster imaging speed,and more compact structure.This study reviewed the progress on the research of biomedical imaging systems based on THz QCL.Furthermore,this study also summarized the advantages of THz bioimaging,THz QCL biomedical imaging,biomedical imaging systems,and biomedical imaging goals.Moreover,the direction of future developments is viewed.

关 键 词：医用光学 太赫兹成像 量子级联 激光器 生物医学 

分 类 号：Q-334[生物学]