基于二值化传输矩阵透过散射介质的光聚焦  

Light Focusing Through Scattering Medium Based on Binary Transmission Matrix

作　　者：斯科 汤黎明[1,2] 杜吉超 吴晨雪 徐晓滨 胡乐佳[1,2] 陈佳佳 龚薇[3] Si Ke;Tang Liming;Du Jichao;Wu Chenxue;Xu Xiaobin;Hu Lejia;Chen Jiajia;Gong Wei(State Key Laboratory of Modern Optical Instrumentation,Department of Neurobiology,the First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,Zhejiang 310058,China;College of Optical Science and Engineering,Zhejiang University,Hangzhou,Zhejiang 310027,China;School of Brain Science and Brain Medicine,Zhejiang University,Hangzhou,Zhejiang 310058,China)

机构地区：[1]浙江大学医学院附属第一医院神经生物学系现代光学仪器国家重点实验室,浙江杭州310058 [2]浙江大学光电科学与工程学院,浙江杭州310027 [3]浙江大学脑科学与脑医学学院,浙江杭州310058

出　　处：《中国激光》2020年第2期394-400,共7页Chinese Journal of Lasers

基　　金：国家自然科学基金(81771877,61975178);浙江省自然科学基金(LZ17F050001,LR20F050002)。

摘　　要：提出一种光透过散射介质的散斑恢复算法,可实现大视场任意位置的聚焦。通过仿真模拟光路测量散射介质的传输矩阵并进行二值化处理,再利用数字微镜器件对入射光进行二值振幅调制,实现透过散射介质的单点或多点聚焦。由于不同聚焦位置的独立性,所提算法能够实现大视场任意位置聚焦。仿真结果表明:聚焦位置的光强增强因子随着采样数目的增加而增加;与传统三步相移法相比,在采样数目减少1/3的情况下,所提算法能够获得55%的增强比,比三步相移法高12%。所提算法对透过散射介质实现大视场范围扫描聚焦有重要意义,在生物医学成像领域具有广阔应用前景。In this paper,a speckle recovery algorithm for light through scattering media that can achieve focusing at any position in a large field of view is proposed.The transmission matrix of the scattering medium is measured and binarized by simulating the optical path,and the digital micro-mirror device is used to modulate the binary amplitude of the incident light to achieve single-point or multi-point focusing through the scattering medium.Due to the independence of different focus positions,the algorithm can achieve large field-of-view focusing at any position.The simulation results show that the intensity enhancement factor of the focus position increases with the increase in the sampling number.Compared with the traditional three-step phase shift method,an enhancement ratio of 55%can be obtained by the proposed algorithm when the number of sampling is reduced by 1/3,which is 12%higher than that by the three-step phase shift method.The proposed algorithm exhibits great significance for realizing large field-of-view scanning and focusing through the scattering medium,making it applicable in the field of biomedical imaging.

关 键 词：生物光学 散射 传输矩阵 贝叶斯定理 聚焦 

分 类 号：O436[机械工程—光学工程]