基于双模态图像信息的眼内激光手术联合标定方法  

Intraocular Laser Surgery Combined Calibration Method Based on Bimodal Image Information

作　　者：杨帆 陈聪 沈超逸 范立成[1] Yang Fan;Chen Cong;Shen Chaoyi;Fan Licheng(School of Mechanical and Electric Engineering,Soochow University,Suzhou,Jiangsu 215301,China)

机构地区：[1]苏州大学机电工程学院,江苏苏州215301

出　　处：《中国激光》2020年第2期418-423,共6页Chinese Journal of Lasers

基　　金：国家自然科学基金(61475108)。

摘　　要：为了获取眼科激光手术中规划手术部位的深度空间信息,搭建了双光纤环形器结构的扫频光相干断层成像(SS-OCT)系统。在样品臂中加入二向色镜,将其与互补金属氧化物半导体(CMOS)相机系统进行整合。对OCT坐标系与相机图像坐标系的几何关系进行匹配,设计了多角度线性扫描、环形扫描等模式,实现了相机视频图像下任意指定位置的多模式扫描成像。该成像系统的纵向分辨率为13.68μm,横向分辨率为29.8μm,在空气中的成像深度为17.25 mm,测量的最大横向偏差为275μm,最大纵向偏差为70μm,能够满足手术的定位要求。该研究初步实现了眼内指定部位深度信息的快速获取,有望应用于眼科疾病诊断和白内障手术导航。In this work, a swept-source optical coherence tomography(SS-OCT) system was constructed using a dual fiber ring structure to obtain the depth spatial information of a planned surgical site in laser ophthalmic surgery. In the proposed system, a dichroic mirror was added to the sample arm to integrate it with a CMOS camera system. After matching the geometric relationship between the coordinates of the OCT system and camera system, several scanning modes, including multi-angle linear scanning and annular scanning, were designed, achieving multimode scanning imaging at any given position of camera video images. The longitudinal resolution of the imaging system was 13.68 μm, while the lateral resolution was 29.8 μm. The imaging depth in the air was 17.25 mm. The measured maximum lateral deviation was 275 μm, and the maximum longitudinal deviation was 70 μm;thus, the requirements of the operation location were met. By using the proposed system, rapid depth information acquisition of the designated parts of the eye is possible. Therefore, the system is suitable for application in ophthalmic disease diagnosis and cataract surgery navigation.

关 键 词：医用光学 眼科激光手术 光相干断层成像系统 定位成像 深度信息 

分 类 号：TN247[电子电信—物理电子学]