老年贫血与其他疾病相关性回顾分析  

Retrospective analysis of the correlation between senile anemia and other basic diseases

作　　者：王权 何慧薇 WANG Quan;HE Hui-wei(Department of Geriatrics,Sir Run Run Hospital,Nanjing Medical University,Nan jing 211166,China)

机构地区：[1]南京医科大学附属逸夫医院老年科,江苏省南京市211166

出　　处：《实用老年医学》2020年第4期352-355,共4页Practical Geriatrics

摘　　要：目的探讨老年贫血与其他基础疾病间的相关性,为提高老年常见疾病预防、诊治和综合管理水平提供临床依据。方法收集2019年2~5月期间我院67例65岁以上住院贫血病人的临床资料,根据不同贫血程度分为轻度贫血组和中重度贫血组。比较2组间其他基础疾病的患病率,筛选出与贫血相关的老年常见疾病。采用多因素Logistic回归分析影响疾病发生的危险因素;利用ROC曲线,分析不同指标对疾病预后的预测价值。结果轻度贫血组与中重度贫血组在脑梗死、CHD患病率方面差异有统计学意义(P <0. 05)。多因素Logistic回归分析结果显示,贫血(OR=1. 044,P=0. 024,95%CI:1. 005~1. 079)和年龄(OR=1. 075,P=0. 042,95%CI:1. 003~1. 152)是老年病人脑梗死的独立危险因素。Hb预测老年脑梗死发生的ROC曲线的AUC为0. 683(P=0. 010,95%CI:0. 554~0. 811);Hb预测老年CHD发生的ROC曲线的AUC为0. 695(P=0. 006,95%CI:0. 569~0. 820)。结论在老年人群中,贫血可能是脑梗死发生的独立危险因素,同时Hb水平对老年脑梗死和CHD的患病风险有一定的预测价值。Objective To explore the correlation between senile anemia and other basic diseases,and to provide reference for improving the prevention,diagnosis and comprehensive management of common diseases in the elderly. Methods The clinical data of 67 inpatients with anemia over 65 years old from February to May 2019 in our hospital were collected and divided into mild anemia group and moderate to severe anemia group according to different levels of anemia. The prevalence of other underlying diseases between the two groups was compared,and the common diseases in the elderly related to anemia were screened. Multivariate Logistic regression was used to analyze the risk factors affecting the occurrence of disease,and receiver operating characteristic(ROC)curve was used to analyze the predictive value of different indicators for disease prognosis. Results The prevalence of cerebral infarction and coronary heart disease between the mild anemia group and the moderate to severe anemia group showed statistically significant difference(P < 0. 05). Multivariate Logistic regression analysis showed that anemia(OR=1. 044,P=0. 024,95%CI:1. 005-1. 079)and age(OR=1. 075,P=0. 042,95%CI:1. 003-1. 152)were independent risk factors for elderly patients with cerebral infarction. The area under the ROC curve of hemoglobin in the elderly patients with cerebral infarction was 0. 683(P=0. 010,95%CI:0. 554-0. 811);The area under the ROC curve of hemoglobin in the elderly patients with coronary heart disease was 0. 695(P=0. 006,95%CI:0. 569-0. 820). Conclusions In the elderly,anemia may be an independent risk factor for the cerebral infarction. The hemoglobin level has a certain predictive value for the risk of cerebral infarction and coronary heart disease in the elderly.

关 键 词：老年人 贫血 脑梗死 冠心病 

分 类 号：R556[医药卫生—血液循环系统疾病]