四川省美沙酮维持治疗新入组患者梅毒感染状况及影响因素分析  

Status of Syphilis Infection and Its Influencing Factors of Patients Newly Admitted to Methadone Maintenance Treatment Clinics in Sichuan Province

作　　者：龚毅[1] 黄惋莉[1] 李恬[1] 曾亚莉[1] 喻航[1] 赖文红[1] GONG Li;HUANG Wangli;LI Tian;ZENG Yali;YU Hang;LAI Wenhong(Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China)

机构地区：[1]四川省疾病预防控制中心,成都610041

出　　处：《预防医学情报杂志》2020年第4期474-480,共7页Journal of Preventive Medicine Information

摘　　要：目的分析美沙酮维持治疗新入组患者的梅毒感染现况及影响因素,为美沙酮维持治疗门诊患者梅毒防治决策提供科学依据。方法回顾性分析2004-2017年四川省49个美沙酮维持治疗门诊新入组患者的一般人口学特征、梅毒感染情况等基本信息,分析不同人口学特征、不同行为特征的美沙酮维持治疗患者梅毒感染率及梅毒感染的影响因素。结果新入组患者共计33218例,梅毒感染率为5.4%,凉山州地区梅毒感染率呈逐年下降趋势,凉山州以外的地区感染率呈逐年上升趋势,其中,2014年最高(8.7%),2004年最低(2.7%)。Logistic回归分析显示,女性,职业为农民和服务业,文盲,未婚,非凉山州地区,戒过毒,近半年吸毒方式为注射和其他方式混用是梅毒感染的危险因素。结论四川省美沙酮维持治疗新入组患者的梅毒感染率高于全国平均水平,尤其女性吸毒人员感染率较高,非凉山地区较凉山地区更为严峻。建议扩大美沙酮治疗的覆盖面,加强利用美沙酮门诊平台对吸毒人群开展梅毒防治的综合干预。Objective To analyze the current status of syphilis infection and its influencing factors in patients newly admitted to methadone maintenance treatment clinics,so as to provide scientific evidence for decision-making of prevention and treatment syphilis in methadone maintenance treatment clinics.Methods The basic demographic characteristics and syphilis infection status of patients newly enrolled in 49 methadone maintenance treatment clinics in Sichuan Province from2004 to 2017 were analyzed retrospectively.The syphilis infection status of patients with different demographic characteristics and different behavioral characteristics was compared.Results A total of33218 patients was enrolled,and the syphilis infection rate was 5.4%.The infection rate of syphilis in Liangshan prefecture decreased year by year,whereas the infection rate outside Liangshan prefecture increased year by year;the highest infection rate(8.7%)was in 2014,whilst the lowest infection rate(2.7%)was in 2014.Logistic regression analysis showed that women,farmers and engaging in service industry,illiterate,unmarried,living in outside of Liangshan prefecture,abstinence,drug use by injection or other ways in the past six months were risk factors for syphilis infection.Conclusion The syphilis infection rate of patients newly admitted to methadone maintenance treatment clinics in Sichuan Province is higher than that of the national average.Particularly,the infection rate of female drug users is higher than of male drug users,and the infection rate outside of Liangshan area is more severe than that of the Liangshan area.The coverage of methadone treatment should be further expanded,and the comprehensive intervention for drug users should be strengthened by using the methadone clinic platform.

关 键 词：美沙酮维持治疗 梅毒 感染率 

分 类 号：R181[医药卫生—流行病学]