隆乳手术的乳腺癌发病风险的累计Meta分析  

Risk of breast cancer related to breast augmentation surgery:a cumulative Meta-analysis

作　　者：李晓霞 周春兰[1] 吴艳妮[1] 胡明钰 LI Xiaoxia;ZHOU Chunlan;WU Yanni;HU Mingyu(Nanfang Hospital,Southern Medical University,Guangdong 510515 China)

机构地区：[1]南方医科大学南方医院,广东510515 [2]南方医科大学

出　　处：《护理研究》2020年第9期1530-1534,共5页Chinese Nursing Research

基　　金：2018年南方医院护理创优——循证实践专项项目,编号:2018EBNc006。

摘　　要：[目的]通过累计Meta分析确定隆乳手术是否会增加女性罹患乳腺癌的风险。[方法]系统检索Cochrane Library、PubMed、Web of Science、EMbase、中国知网、维普数据库、万方数据库,检索时间为建库至2019年3月。使用I2评估统计异质性,基于研究中的异质性检验选择固定或随机效应模型。使用Egger回归不对称检验估计发表偏倚。[结果]共纳入研究9项,其中包含队列研究8篇,病例对照研究1篇,总样本量达49495人,研究结果显示隆乳手术不会增加女性乳腺癌的发病风险。[结论]现有证据不支持隆乳手术会增加女性乳腺癌的发病风险,尚需更多的原始研究进一步验证。Objectives:To determine whether breast augmentation surgery could increase the risk of breast cancer in women through a cumulative Meta-analysis.Methods:Cochrane Library,PubMed,Web of Science,EMbase,CIKI,VIP and Wanfang database were systematically searched,the searching time was from database established to March 2019.Statistical heterogeneity was assessed using I^2 statistics,and fixed or random effects models were selected based on heterogeneity testing in the study.The publication bias was estimated using the Egger regression asymmetry test.Results:A total of 9 studies were included,including 8 cohort studies and 1 casecontrol study,involving 49495 cases.The results showed that breast augmentation surgery would not increase the risk of breast cancer.Conclusion:The current evidence didn’t support that breast augmentation surgery could increase the risk of breast cancer in women,and more original studies are needed to confirm it.

关 键 词：隆乳手术 乳腺癌 随访 累计Meta分析 

分 类 号：R47[医药卫生—护理学]