通心络胶囊治疗非ST段抬高型急性心肌梗死的效果及对心肌组织灌注水平的影响  

Effects of Tongxinluo Capsule on Non-ST-segment Elevation Acute Myocardial Infarction and Its Influence on Myocardial Tissue Perfusion Level

作　　者：孙炳克 SUN Bing-ke(Department of Cardiology,Shaoling District People’s Hospital of Luohe City,Luohe 462000,Henan Province,China)

机构地区：[1]河南省漯河市召陵区人民医院心内科,河南漯河462000

出　　处：《罕少疾病杂志》2020年第1期8-10,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨通心络胶囊治疗非ST段抬高型急性心肌梗死(NSTEMI)的效果及对心肌组织灌注水平的影响。方法 2017年2月-2018年4月我院收治的100例NSTEMI患者,按照随机数表法分为观察组及对照组各50例,对照组给予常规抗心肌缺血治疗及抗凝治疗,观察组在对照组基础上加服通心络胶囊。比较两组临床总有效率、冠状动脉造影TIMI血流分级及并发症情况。结果观察组临床总有效率为88.00%明显高于对照组66.00%(P<0.05);观察组TIMI分级中0级、1级比例较对照组明显减少,2级、3级比例较对照组明显增加(P<0.05);观察组并发症总发生率20.00%与对照组总发生率24.00%差异不显著(P>0.05)。结论应用通心络胶囊治疗NSTEMI能够有效提高患者疗效,改善心肌组织灌注水平,并发症较少。Objective To explore the effects of Tongxinluo capsule on non-ST-segment elevation acute myocardial infarction(NSTEMI) and its influence on myocardial tissue perfusion level. Methods 100 patients with NSTEMI admitted to our hospital from February 2017 to April 2018 were divided into observation group and control group according to the random number table method, with 50 cases in each group. Control group was given conventional anti-myocardial ischemia therapy and anticoagulant therapy, and observation group was given Tongxinluo capsule on the basis of control group. The total clinical effective rate, coronary angiography TIMI blood flow grading and complications were compared between the two groups. Results The total clinical effective rate in observation group was significantly higher than that in control group(88.00% vs 66.00%)(P<0.05). The proportions of grade 0 and grade 1 of TIMI in observation group were significantly decreased compared with those in control group while the proportions of grade 2 and grade 3 were significantly increased compared with those in control group(P<0.05). The total incidence rate of complications in observation group was not significantly different from that in control group(20.00% vs 24.00%)(P>0.05). Conclusion Tongxinluo capsule for NSTEMI can effectively improve the efficacy and improve myocardial tissue perfusion level, and it has few complications.

关 键 词：通心络胶囊 非ST段抬高型急性心肌梗死 心肌组织灌注 

分 类 号：R542.2[医药卫生—心血管疾病]