A boronic acid-based fluorescent hydrogel for monosaccharide detection  

作　　者：Suying Xu Adam C.Sedgwick Souad A.Elfeky Wenbo Chen Ashley S.Jones George T.Williams A.Toby A.Jenkins Steven D.Bull John S.Fossey Tony D.James 

机构地区：[1]Department of Biochemistry,Faculty of Science,Beijing University of Chemical Technology,Beijing 100029,China [2]Department of Chemistry,University of Bath,Bath BA27AY,UK [3]Department of Chemistry,University of Texas at Austin,TX 78712-1224,USA [4]School of Chemistry,University of Birmingham,Birmingham B152TT,UK [5]National Institute of Laser Enhanced Sciences,Cairo University,Giza 12613,Egypt [6]Higher Institute for Optics Technology,Sheraton,Cairo 17361,Egypt [7]Shanghai Key Laboratory of Materials Protection and Advanced Materials in Electric Power,Shanghai University of Electric Power,Shanghai 200090,China

出　　处：《Frontiers of Chemical Science and Engineering》2020年第1期112-116,共5页化学科学与工程前沿（英文版）

基　　金：grateful for the support of the EPSRC and DTI(DT/F00267X/1);the Leverhulme Trust for support(F00094BC);the JDRF(2-SRA-2016-267-A-N)for support.

摘　　要：A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection.In solution,the fluorescent probe displayed a strong fluorescence turn-on response upon exposure to fructose,and an expected trend in apparent binding constants,as judged by a fluorescence response where D-fructose>D-galactose>D-mannose>D-glucose.The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of D-fructose resulting in a 10-fold enhancement(≤0.25 mol/L).

关 键 词：BORON HYDROGEL MONOMER 

分 类 号：O62[理学—有机化学]