医疗机构丙型肝炎诊断治疗现况研究  

Current status of hepatitis C diagnosis and treatment in Chinese medical institutions

作　　者：冯小飞 丁国伟[1] 俞海亮[1] 潘玲 高榆 汤杨 毛宇嵘[1] 庞琳[1] FENG Xiaofei;DING Guowei;YU Hailiang;PAN Ling;GAO Yu;TANG Yang;MAO Yurong;PANG Lin(National Center for A1DS/STD Control and Prevention,Chinese Center for Disease Center and Prevention,Beijing 102206,China)

机构地区：[1]中国疾病预防控制中心,性病艾滋病预防控制中心,北京102206

出　　处：《中国艾滋病性病》2020年第3期247-249,共3页Chinese Journal of Aids & STD

摘　　要：目的分析目前我国医疗机构丙型肝炎(简称"丙肝")诊断治疗能力及有关工作情况。方法选取14个省(自治区、直辖市)56个县区的当地居民就诊较多的二级及以上医院为调查对象,采用横断面调查方式,了解医院基本情况、开展丙肝病毒(HCV)抗体检测、HCV核酸检测及丙肝治疗情况等,并对不同级别的医院进行比较。结果共调查76家医院,均开展HCV抗体检测项目,HCV抗体检测率为48.4%,二级医院HCV抗体检测率(59.9%)高于三级医院(40.7%)。35家(46.1%)医院开展HCV核酸检测项目,HCV核酸检测率为34.9%,二级医院HCV核酸检测率(21.2%)低于三级医院(65.3%)。32家(42.1%)对丙肝患者开展治疗,但仅8家(10.5%)能提供规范诊断及治疗方案,规范诊疗率仅11.8%(1 150/9 723)。结论本次所调查医疗机构普遍具备HCV抗体检测能力,但提供HCV核酸检测服务的医院不足半数,二级医院HCV核酸检测率明显低于三级医院;丙肝规范诊疗率低下,亟待加强有关能力建设。Objective To analyze the current status of diagnosis and treatment of hepatitis C in Chinese medical institutions. Methods A cross-sectional study was conducted to collect and analyze the basic information and data on anti-HCV test, HCV RNA test and HCV therapy in 76 secondary or tertiary hospitals in 56 counties/districts of 14 provinces. Results All hospitals provided anti-HCV testing and the rate of anti-HCV test among in-patients was 48.4%, with 59.9% in secondary hospitals higher than 40.7% in tertiary hospitals. HCV RNA testing was provided in 35(46.1%) hospitals, and 34.9% of HCV RNA test was among in-patients, with 21.2% in secondary hospitals lower than 65.3% in tertiary hospitals. 32(42.1%) hospitals provided HCV treatment and only 8(10.5%) could provide standardized diagnosis and treatment services for HCV patients, with 11.8%(1 150/9 723) of standardized diagnosis and treatment. Conclusion All hospitals have the ability of providing anti-HCV testing. However, less than half of them is able to provide HCV RNA testing. HCV RNA test rate in secondary hospitals is lower than that in tertiary hospitals. The rate of standardized HCV diagnosis and treatment is relatively low, and it is necessary to further strengthen the capacity building on HCV diagnosis and treatment in China.

关 键 词：丙型肝炎 诊断 抗病毒治疗 

分 类 号：R512.6[医药卫生—内科学]