胰岛素泵强化治疗对初治2型糖尿病的疗效及预后  

The Efficacy and Prognosis of Intensive Insulin Pump Therapy for Newly Diagnosed Type 2 Diabetes

作　　者：饶湖英[1] 吴一行[1] 肖文霞[1] 阙凤连[1] RAO Hu-ying;WU Yi-hang;XIAO Wen-xia(Department of Endocrinology,The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 511447,Guangdong Province,China)

机构地区：[1]广州医科大学附属第二医院内分泌科,广东广州511447

出　　处：《罕少疾病杂志》2020年第2期41-43,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探析胰岛素泵强化治疗对初治2型糖尿病的疗效及对预后的影响。方法将2017年8月到2018年12月我院收治的120例初治2型糖尿病患者作为主要研究对象,采用数字随机表法将其分为两组,60例/组。对照组采用胰岛素皮下注射强化治疗,观察组采用胰岛素泵强化治疗,比较两组患者治疗前后的血糖变化情况和预后相关指标。结果治疗后两组患者的空腹血糖、餐后2h血糖、糖化果糖胺水平均明显低于治疗前,且观察组明显低于对照组,有显著差异;两组患者治疗后的胰岛素抵抗指数均低于治疗前,且观察组低于对照组,差异显著;观察组患者的血糖达标时间短于对照组,胰岛素用量少于对照组,组间比较存在显著差异;观察组的低血糖发生率显著低于对照组,有显著差异(P<0.05)。结论采用胰岛素泵强化治疗对初治2型糖尿病患者而言效果显著,能够降低患者的血糖值,缩短血糖达标时间,减少胰岛素的剂量,且预后佳,更值得进一步推广应用。Objective To investigate the effect of intensive insulin pump therapy on newly diagnosed type 2 diabetes mellitus and its effect on prognosis. Methods A total of 120 patients with newly diagnosed type 2 diabetes admitted to our hospital from August 2017 to December 2018 were divided into two groups, 60 patients/group. The control group was treated with intensive insulin injection, and the observation group was treated with intensive insulin pump. The changes of blood glucose and prognosis in the two groups were compared before and after treatment. Results After treatment, fasting blood glucose, postprandial 2 h blood glucose, and glycosylated fructosamine levels were significantly lower than those before treatment, and the observation group was significantly lower than the control group. There were significant differences. The insulin resistance index of the two groups was low after treatment. Before treatment, and the observation group was lower than the control group, the difference was significant;the blood glucose compliance time of the observation group was shorter than that of the control group, the insulin dosage was lower than that of the control group, and there was significant difference between the groups;the incidence of hypoglycemia in the observation group was significant. There was a significant difference(P<0.05) between the control group and the control group. Conclusion The intensive treatment with insulin pump is effective for patients with newly diagnosed type 2 diabetes. It can reduce the blood sugar level of patients, shorten the time of blood glucose compliance, reduce the dose of insulin, and has a good prognosis. It is worth further promotion.

关 键 词：胰岛素泵 强化治疗 初治2型糖尿病 疗效 预后 

分 类 号：R587.1[医药卫生—内分泌] R781.64[医药卫生—内科学]