Hydrothermal growth of hydroxyapatite and ZnO bilayered nanoarrays on magnesium alloy surface with antibacterial activities  

作　　者：Mengke Peng Fenyan Hu Minting Du Bingjie Mai Shurong Zheng Peng Liu Changhao Wang Yashao Chen 

机构地区：[1]Key Laboratory of Applied Surface and Colloid Chemistry(Ministry of Education),School of Chemistry and Chemical Engineering,Shaanxi Normal University,Xi’an,710119,China [2]Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry(Ministry of Education),National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China,College of Life Sciences,Shaanxi Normal University,Xi’an,710119,China [3]Key Laboratory of Biorheological Science and Technology of Ministry of Education,Chongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing,College of Bioengineering,Chongqing University,Chongqing,400044,China

出　　处：《Frontiers of Materials Science》2020年第1期14-23,共10页材料学前沿（英文版）

基　　金：This work was financially supported by the National Natural Science Foundation of China(Grant Nos.21773149,21273142 and 21703132);the Program for Changjiang Scholars and Innovative Research Team in University(IRT14R33);the Key Research and Development Project of Shaanxi Province of China(No.2018GY-117);the Natural Science Foundation of Shaanxi Province of China(2019JQ161);the Fundamental Research Funds for the Central Universities(GK201802001).

摘　　要：Magnesium alloy(MgA)has been extensively used as orthopedic and cardiovascular scaffolds in virtue of its good biocompatibility,unique biodegradability and excellent mechanical properties.However,poor corrosion resistance and easy infection after implantation seriously limit the potential applications of MgA in the biomedical field.Herein,we fabricated bilayered nanoarrays of hydroxyapatite nanorods(HANRs)and ZnO nanorods(ZnONRs)onto the surface of MgA(MgA-MgO-HANRs-ZnONRs)via micro-arc oxidation(MAO)treatment,microwave-assisted hydrothermal and hydrothermal methods.The morphology and chemical composition of MgA-MgO-HANRs-ZnONRs was characterized by FE-SEM,XRD and EDS,indicating that HANRs-ZnONRs bilayered nanoarrays were fabricated on the surface of MgA-MgO.The surface of MgA-MgO-HANRs-ZnONRs exhibited excellent hydrophilicity as evidenced by the low water contact angle of 3°.Compared with the original MgA,the corrosion resistance of MgA-MgO-HANRs-ZnONRs was obviously improved with decreasing the corrosive current density(icorr)of 2 orders of magnitude.The MgA-MgO-HANRs-ZnONRs performed excellent antibacterial properties with the bactericidal rate of 96.5%against S.aureus and 94.3%against E.coli.

关 键 词：MAGNESIUM alloy nanoarray HYDROTHERMAL synthesis ANTIBACTERIAL activity corrosion resistance 

分 类 号：TG146.22[一般工业技术—材料科学与工程]