难辨性新型冠状病毒肺炎的家庭病例报告  

Latent corona virus disease 2019:a report of family cases

作　　者：贺星星[1] 杨涛[2] 于晓娜 周伟 傅一牧 封启明[1] He Xingxing;Yang Tao;Yu Xiaona;Zhou Wei;Fu Yimu;Feng Qiming(Department of Emergency,the Sixth People's Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200233,China;Department of Emergency,Jinshan Branch of the Sixth People's Hospital of Shanghai,Shanghai 201599,China)

机构地区：[1]上海交通大学附属第六人民医院急诊医学科,200233 [2]上海市第六人民医院金山分院急诊科,201599

出　　处：《中国中西医结合急救杂志》2020年第2期210-212,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

摘　　要：由于新型冠状病毒肺炎(简称新冠肺炎)具有较强的传染性和传播途径的难辨性,许多患者在不知不觉的情况下被感染,或高度疑似的患者因新型冠状病毒(2019-nCoV)核酸检测阴性而无法确诊.2020年1月17日,上海交通大学附属第六人民医院收治1例67岁女性术后重症肺炎患者,该患者无明确的流行病学接触史,但其临床表现及肺部影像学高度疑似新冠肺炎,然而连续3次2019-nCoV核酸检测均为阴性.其丈夫在医院照顾患者,曾多次往返于医院等公共场所,虽然没有明确的新冠肺炎患者接触史,但于2020年1月29日出现发热伴乏力,同日2019-nCoV核酸检测阳性,确诊为新冠肺炎.儿子同父亲母亲均有密切接触,在父亲确诊后也出现全身酸痛等不适症状,但肺部CT未见明显异常,1月29日2019-nCoV核酸检测阴性.分析该家庭3例聚集性病例,提示我们需综合考虑患者临床表现、肺部影像学、2019-nCoV核酸检测结果,为疫情防控中确诊或疑似新冠肺炎患者的管理提供更多信息.Due to the high infectivity and latent transmission route of corona virus disease 2019(COVID-19),many patients are infected under insensible conditions,or highly suspected patients cannot be diagnosed because of the negative nucleic acid test of 2019 novel coronavirus(2019-nCoV).A 67-year-old female patient with severe pneumonia after operation was admitted to the Sixth People's Hospital Affiliated to Shanghai Jiao Tong University on January 17,2020.The patient had no clear history of epidemiological exposure,but was highly suspected of COVID-19 based on her clinical manifestations and chest CT imaging.However,2019-nCoV nucleic acid tests were negative for three consecutive times.Her husband,a 67-year-old male,made multiple trips to the hospital and other public places,and also did not have a clear contact history with COVID-19 patients.He developed fever and fatigue on January 29,2020,and was diagnosed as COVID-19 on the same day according to positive 2019-nCoV nucleic acid test.Their son,had close contact with both the father and mother,and felt aches and pains all over the body after his father confirmed diagnosis.However,his chest CT showed no obvious abnormality,and the 2019-nCoV nucleic acid test was negative.Combined with the analysis of three cases in this family,it is suggested that we can provide more information for the management of confirmed or suspected COVID-19 patients in epidemic prevention and control through comprehensively analyzing the patients'clinical manifestations,pulmonary imaging and viral nucleic acid detection.

关 键 词：新型冠状病毒肺炎 临床表现 肺部影像学 

分 类 号：S85[农业科学—兽医学]