仿生各向异性聚(N-异丙基丙烯酰胺)水凝胶智能响应驱动器的研究进展  

Progress of Biomimetic Anisotropic Poly(N-isopropylacrylamide)Intelligent Response Actuators

作　　者：严昊 唐萍 李书宏[2] 赵天艺 刘明杰 YAN Hao;TANG Ping;LI Shuhong;ZHAO Tianyi;LIU Mingjie(Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education,School of Chemistry,Beihang University,Beijing 100191,China;School of Science,Beijing Technology and Business University,Beijing 100048,China;Beijing Advanced Innovation Center for Biomedical Engineering,Beihang University,Beijing 100191,China)

机构地区：[1]北京航空航天大学化学学院,仿生智能界面科学与技术教育部重点实验室,北京100191 [2]北京工商大学理学院,北京100048 [3]北京航空航天大学生物医学工程高精尖创新中心,北京100191

出　　处：《高等学校化学学报》2020年第5期936-946,共11页Chemical Journal of Chinese Universities

基　　金：国家杰出青年科学基金(基金号:21725401)资助.

摘　　要：各向异性水凝胶在外界的响应刺激下可以具有不同的反应机制与驱动过程.本文综述了近期基于PNIPAM水凝胶智能响应驱动器的设计方法,总结了多种各向异性结构对驱动性能的影响,并对该领域所面临的挑战进行了讨论.A hydrogel is a three-dimensional network of hydrophilic polymers,which can hold a large amount of water while maintaining the structure.Due to its"soft"and"wet"characteristics,the resemblance to living tissue opens up many opportunities for applications in biomedical areas.However,compared with soft tissues,traditional hydrogels have rather weak mechanical properties due to the uneven cross-linking structures during polymerizations.Also,the mechanical properties of the hydrogels are isotropic,as oppose to most of the soft tissues,which are always anisotropic.Many soft tissues in nature are composed of multi-level anisotropic structures,which give animals the abilities to adapt changes in the harsh environment.Inspired by the anisotropic structure in nature,how to introduce highly ordered structures into hydrogel networks has become a hot research topic in recent years.Among the thermos-responsive polymers,poly(N-isopropylacrylamide)(PNIPAM)is the most important one because of transition across the lower critical solubility temperature(LCST).This unique property endows PNIPAM the ability to be used as smart actuators.In this review,several strategies of fabricating anisotropic PNIPAM-based smart actuators are summarized,and the impact of anisotropic structures on their actuating abilities are discussed in detail.

关 键 词：水凝胶 聚(N-异丙基丙烯酰胺) 生物组织 各向异性 有序结构 智能响应驱动器 

分 类 号：O631[理学—高分子化学] O648.17[理学—化学]