氨基醇杂多酸类离子液体催化环酮的Baeyer-Villiger氧化反应  

Baeyer-Villiger Oxidation of Cyclic Ketones Catalyzed by Amino Alcohol Heteropoly Acid Ionic Liquid

作　　者：高崇 于凤丽[1] 解从霞[1] 于世涛[2] GAO Chong;YU Fengli;XIE Congxia;YU Shitao(State Key Laboratory Base of Eco-chemical Engineering,College of Chemistry and Molecular Engineering,2.College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,China)

机构地区：[1]青岛科技大学化学与分子工程学院生态化工国家重点实验室培育基地,青岛266042 [2]青岛科技大学化工学院,青岛266042

出　　处：《高等学校化学学报》2020年第5期1101-1107,共7页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:21878166);山东省重点研发计划(公益类专项)项目(批准号:2017GGX70102);山东省泰山学者计划项目(批准号:ts201511033)资助.

摘　　要：合成了一系列氨基醇杂多酸类离子液体,并将其用于催化环酮的Baeyer-Villiger氧化反应.以2-庚基环戊酮为模板底物,H2O2为氧化剂,探究了此类氨基醇杂多酸类离子液体的催化活性,筛选出催化活性最高的催化剂为[Pro-ps]H2PW12O40,最佳反应条件:n(2-庚基环戊酮)∶n(催化剂)∶n(H2O2)=1∶0.03∶4,反应温度40℃,反应时间8 h,无溶剂.在最佳条件下,2-庚基环戊酮的转化率为98.19%,产物δ-十二内酯的选择性可达82.84%.水相中的离子液体[Pro-ps]H2PW12O40经干燥后可以重复使用.经过5次循环使用后催化活性未见明显下降.[Pro-ps]H 2PW12O40还可用于催化其它多种环酮的Baeyer-Villiger氧化反应,结果表明,该催化剂具有良好的重复使用性和底物普适性.A series of amino alcohol heteropolyacid ionic liquids was synthesized and used to catalyze the Baeyer-Villiger oxidation of cycloketones.2-Heptylcyclopentanone was used as a template substrate and H 2O 2 was used as an oxidant.The catalytic activity of such amino alcohol heteropoly acid ionic liquids was investigated.The catalyst with the highest catalytic activity was[Pro-ps]H 2PW 12 O 40.The obtained optimum reaction conditions were n(2-heptylcyclopentanone)∶n(catalyst)∶n(H 2O 2)=1∶0.03∶4 at 40℃for 8 h by solvent free.Under the optimum conditions,the conversion rate of 2-heptylcyclopentanone was 98.19%,and the selectivity ofδ-dodelactone was up to 82.84%.After simple treatment,the ionic liquid[Pro-ps]H 2PW 12 O 40 could be reused,and the catalytic activity did not decrease significantly after five cycles.[Pro-ps]H 2PW 12 O 40 could also be used to catalyze the Baeyer-Villiger oxidation of various cyclic ketones.The results showed that the catalyst had good reusability and substrate adaptability.

关 键 词：氨基醇离子液体 杂多酸 BAEYER-VILLIGER氧化 环酮 内酯 

分 类 号：O643[理学—物理化学] O621[理学—化学]