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作 者:邢俊领[1] 许国栋[1] 武莉娜[1] 赵家鹏[1] 王玉峰[1] Xing Junling;Xu Guodong;Wu Lina(Department of Neurosurgery,The Third Hospital Affiliated to Xinxiang Medical College)
机构地区:[1]新乡医学院第三附属医院神经外科,453003
出 处:《长治医学院学报》2020年第2期126-129,共4页Journal of Changzhi Medical College
摘 要:目的:探讨微血管减压(MVD)与经皮穿刺球囊压迫(PBC)治疗三叉神经痛的临床疗效。方法:选取92例三叉神经痛患者为受试对象,根据治疗方法不同分为MVD组与PBC组,各46例;MVD组患者实施MVD手术治疗,PBC组患者给予PBC手术治疗。比较2组患者临床指标(出血量、住院时间、手术时间)及术前、术后6个月巴罗神经学研究所(BNI)三叉神经痛评分、健康促进生活方式量表(HPLP)评分,并记录相关并发症发生率(面目麻木、咬肌无力、口角疱疹)。结果:PBC组患者出血量、住院时间、手术时间等临床指标均低于MVD组(P<0.05)。2组患者治愈率及有效率比较差异无统计学意义,MVD组患者术后复发率(2.17%)明显低于PBC组(19.57%),差异有统计学意义(P<0.05);2组患者HPLP各项评分较术前均有提高,且MVD组明显高于PBC组(P<0.05)。术后6个月,MVD组并发症总发生率(2.17%)明显低于PBC组(58.70%),差异有统计学意义(P<0.05)。结论:MVD与PBC均可改善患者三叉神经痛症状,缓解疼痛;MVD术后并发症发生率低,生活质量改善效果好;PBC住院时间及手术时间短,适合于高龄患者。Objective: To explore the clinical efficacy of microvascular decompression(MVD) and percutaneous balloon compression(PBC) in the treatment of trigeminal neuralgia. Methods: A total of 92 patients with trigeminal neuralgia were selected as subjects, and were divided into MVD group and PBC group according to different treatment methods, 46 cases in each group. Observation group received MVD surgery while control group received PBC surgery. The clinical indicators(bleeding volume, hospital stay, operative time), and pain level [Barrow Neurological Institute(BNI) Trigeminal Neuralgia Rating Scale] and quality of life [Health Promoting Lifestyle Profile(HPLP)] before operation and at 6 months after operation, and the incidence rates of related complications(facial numbness, masseter muscle weakness, herpes zoster of angulus oris) were compared between the two groups. Results: Patients in the PBC group had lower clinical indicators such as bleeding volume, length of hospital stay, and operation time than those in the MVD group(P<0.05). There was no significant difference in cure and effective comparison between the two groups. The postoperative recurrence rate of patients in the MVD group(2.17%) was significantly lower than that in the PBC group(19.57%)(P<0.05);the HPLP scores of the two groups were significantly higher than those before surgery, and the MVD group was significantly higher than PBC group(P<0.05). At 6 months after operation, the overall incidence of complications in the MVD group(2.17%) was significantly lower than that in the PBC group(58.70%)(P<0.05). Conclusion: Both MVD and PBC can improve the symptoms of trigeminal neuralgia and alleviate the pain of disease. MVD has lower incidence rate of postoperative complications and better quality of life of patients;PBC has shorter hospital stay and operative time, which is suitable for elderly patients.
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