PLR、Cav1、CXCL12与急性缺血性卒中患者出现END的相关性研究及END危险因素分析  

Study on the correlation between PLR,Cav1,CXCL12 and END in patients with acute ischemic stroke and analysis of END risk factors

作　　者：吴雅莉[1] 吴春农[1] WU Yali;WU Chunnong(Emergency department of the first peopled Hospital of Liangshan,615000)

机构地区：[1]凉山州第一人民医院急诊科,四川凉山615000

出　　处：《中国急救复苏与灾害医学杂志》2020年第4期426-428,共3页China Journal of Emergency Resuscitation and Disaster Medicine

摘　　要：目的分析PLR、Cav1、CXCL12与急性缺血性卒中患者出现END的相关性及END危险因素。方法选择2017年3月-2019年2月在凉山州第一人民医院进行治疗的急性缺血性脑卒中患者98例作为研究对象,根据是否发生END分为A组(END组)和B组(非END组)。对两组患者PLR、Cav1、CXCL12水平进行测定。结果A组患者PLR,Cav1和CXCL12水平均显著高于B组,统计学分析结果表明差异显著(P<0.05)。A组患者NIHSS评分高于B组,GCS评分低于B组,差异有统计学意义(P<0.05)。分析结果表明,Cav1≥8.2 ng/mL,PLR≥123.12,NIHSS评分,GCS评分为END发生的独立预测因子(P<0.05)。结论Cav1≥8.2ng/mL,PLR≥123.12,NIHSS评分,GCS评分为END发生的独立危险因素。objective To analyze the correlation between PLR,Cavl,CXCL12 and END in patients with acute ischemic stroke and the risk factors of END.Methods 98 patients with acute ischemic stroke treated in Liangshan First People's Hospital from March 2017 to February 2019 were divided into group A(END group)and group B(non-END group)according to the occurrence of END.The levels of PLR,Cav1,CXCL12 in the two groups were measured.Results the levels of PLR,Cav1 and CXCL12 in group A were significantly higher than those in group B.the results of statistical analysis showed that the NIHSS score of group A was higher than that of group B,and the score of GCS was lower than that of group B(P<0.05).The results showed that Cav1≥18.2 ng/mL,PLR≥123.12 and GCS score were independent predictors of END.Conclusion Cav1≥18.2 ng/mL,PLR≥123.12,NiHSS score and GCS score are independent risk factors for END.

关 键 词：PLR Cav1 CXCL12 急性缺血性卒中 END 相关性 危险因素 

分 类 号：R442.7[医药卫生—诊断学]