西格列汀联合预混胰岛素治疗脆性糖尿病伴高脂血症疗效  

Effect of Sitagliptin Combined with Premixed Insulin in the Treatment of Fragile Diabetes with Hyperlipidemia

作　　者：李燕 LI Yan(Department of Gastroenterology,People's Hospital of Ledu District,Haidong,Qinghai Province,810700 China)

机构地区：[1]青海省海东市乐都区人民医院消化内科,青海海东810700

出　　处：《糖尿病新世界》2020年第2期84-85,共2页Diabetes New World Magazine

摘　　要：目的分析西格列汀联合预混胰岛素治疗脆性糖尿病伴高脂血症的疗效。方法按照随机抽样的方式,从该院2018年3月—2019年3月的脆性糖尿病伴高脂血症患者中,选取110例作为研究对象。对患者的临床资料进行整理,确定其完备性后,按照双色球分组的方式将其划分为两组——对照组(n=55)和观察组(n=55),前者采取单纯的预混胰岛素治疗,后者采取西格列汀联合预混胰岛素治疗。对两组患者治疗前、持续用药12周以后的血糖指标与血脂指标进行观察。结果两组患者治疗前的血糖指标与血脂指标比较,差异无统计学意义(P>0.05);在治疗后,观察组患者与对照组患者的血糖指标与血脂指标相比较,差异有统计学意义(P<0.05)。结论西格列汀联合预混胰岛素治疗脆性糖尿病伴高脂血症的临床效果较好,能够对患者的血糖与血脂水平进行调整,且安全性较高,值得推广。Objective To analyze the efficacy of sitagliptin combined with premixed insulin in the treatment of fragile diabetes with hyperlipidemia.Methods According to the random sampling method,110 patients with brittle diabetes mellitus and hyperlipidemia from the hospital from March 2018 to March 2019 were selected as the research subjects.After the patient's clinical data were sorted out and their completeness was determined,they were divided into two groups according to the two-color ball grouping method:the control group(n=55)and the observation group(n=55).The former adopted pure premixed insulin treatment,the latter was treated with sitagliptin in combination with premixed insulin.The blood glucose index and blood lipid index of the two groups of patients before and after 12 weeks of treatment were observed.Results There was no statistically significant difference in blood glucose index and blood lipid index between the two groups(P>0.05).After treatment,the blood glucose index and blood lipid index of the observation group and the control group were statistically significant(P<0.05).Conclusion Sitagliptin combined with premixed insulin is effective in the treatment of fragile diabetes with hyperlipidemia.It can adjust the blood glucose and blood lipid levels of patients,and it is safe and worth promoting.

关 键 词：西格列汀 预混胰岛素 脆性糖尿病 高脂血症 疗效 

分 类 号：R587[医药卫生—内分泌]