如何根据特异性IgM和IgG评价新型冠状病毒宫内垂直传播  

How to obtain evidence of vertical transmission of coronavirus according to serological test of specific IgM and IgG antibodies

作　　者：王晨[1] 周乙华[2] 杨慧霞[1] Wang Chen;Zhou Yihua;Yang Huixia(Department of Obstetrics and Gynecology,Peking University First Hospital,Beijing 100034,China;Department of Infectious Diseases,Drum Tower Hospital Affiliated to Medical College of Nanjing University,Nanjing 210008,China)

机构地区：[1]北京大学第一医院妇产科,100034 [2]南京大学医学院附属鼓楼医院感染疾病科,210008

出　　处：《中华围产医学杂志》2020年第4期217-219,共3页Chinese Journal of Perinatal Medicine

摘　　要：新型冠状病毒能否通过宫内垂直传播感染胎儿是关注的焦点,而如何正确评价新型冠状病毒是否存在宫内垂直传播,更是问题的关键所在。病毒学和血清学证据对诊断病毒宫内垂直传播都有价值。单纯将血清学结果用于确定新型冠状病毒宫内传播时,应至少对新生儿随访3~6个月,动态观察IgM和IgG滴度变化,同时随访其母亲,与母亲特异性抗体的滴度进行比较。Whether 2019 novel coronavirus can be vertically transmitted to fetuses is a major concern,while how to obtain evidence of vertical transmission in viral infected pregnant women is the key.Virological and serological evidence is valuable to clarify this issue.However,longitudinal follow-up of infants for at least 3-6 months after birth and dynamic changes of specific antibodies of the mothers is essential when serological results are used to confirm or exclude vertical transmission.

关 键 词：冠状病毒感染 传染性疾病传播 垂直 免疫球蛋白M 免疫球蛋白G 

分 类 号：R563.1[医药卫生—呼吸系统]