激光工艺参数对离体皮肤显微组织特征的影响  

Effect of Laser Processing Parameters on Microstructural Characteristics of Skin in vitro

作　　者：陈子博 黄俊[1,2] 王克鸿[1,2] 陈雨昕 严龙 Chen Zibo;Huang Jun;Wang Kehong;Chen Yuxin;Yan Long(School of Material Science and Engineering,Nanjing University of Science and Technology,Nanjing,Jiangsu 210094,China;Key Laboratory for Controlled Arc Intelligent Additive Technology,Ministry of Industry Informatization,Nanjing University of Science and Technology,Nanjing,Jiangsu 210094,China)

机构地区：[1]南京理工大学材料科学与工程学院,江苏南京210094 [2]南京理工大学受控电弧智能增材技术工业和信息化部重点实验室,江苏南京210094

出　　处：《中国激光》2020年第3期98-105,共8页Chinese Journal of Lasers

基　　金：总装预研基金资助项目(7131532)。

摘　　要：将数字图像处理技术中的纹理特征分析方法引入到激光生物焊接中,深入分析激光焊接离体皮肤显微组织的变化,以基于灰度共生矩阵计算所得的二阶统计特征量作为表征离体皮肤显微组织特征的主要量化指标,通过响应面法分析得到了各激光参数以及它们之间的交互作用对激光焊接离体皮肤显微组织纹理特征的影响规律。研究结果表明:激光扫描速度是影响离体皮肤焊后显微组织的主要因素,且对角二阶矩、相关性、熵、对比度这4个纹理特征参数都有显著影响;激光功率及其与扫描速度的交互作用对角二阶矩、相关性、熵有显著影响。This paper introduced the texture feature analysis method in digital image processing technology into laser biological tissue welding, and the microstructural changes of laser-welded skin in vitro were deeply analyzed. The second-order statistical features calculated using gray co-occurrence matrix were used as primary quantitative indexes to characterize the microstructural characteristics of isolated skin. The effects of laser parameters and their interaction on the microstructural and texture characteristics of laser-welded skin in vitro were obtained using a response surface method. The results show that the laser scanning speed is the key factor that affects the microstructure of isolated skin subsequent to welding, and the angular second moment, correlation, entropy, and contrast have significant effects on the texture feature parameters. Furthermore, the laser power and the interaction between laser power and welding speed have significant effects on the angular second moment, correlation, and entropy.

关 键 词：激光技术 激光生物焊接 显微组织 灰度共生矩阵 响应面法 图像处理 

分 类 号：TN249[电子电信—物理电子学]