东茛菪碱与地塞米松联合治疗在急性中毒性肺水肿抢救中的临床分析  

Clinical Analysis of Combined Treatment of Scopolamine and Dexame thasone in Acute Toxic Pulmonary Edema

作　　者：王华德 桑运春 WANG Hua-de;SANG Yun-chun(Department of General Surgery,Feixian People's Hospital,Linyi,Shandong Province,273400China)

机构地区：[1]费县人民医院普外科,山东临沂273400

出　　处：《中外医疗》2020年第4期112-114,共3页China & Foreign Medical Treatment

摘　　要：目的观察东茛菪碱与地塞米松联合治疗在急性中毒性肺水肿抢救中的临床分析。方法方便选取该院2016年1月-2018年12月期间收治的急性中毒性肺水肿患者行常规治疗配合东茛菪碱与地塞米松联合抢救总计80例,随机分为观察组和对照组。通过观察两组患者治疗时治疗起效时间、水肿消失时间、治疗前后血气指标水平与住院时间,治疗效果与预后。结果经治后实验组患者血气指标水平明显优于对照组,而实验组患者治疗起效时间、水肿消失时间与住院时间明显少于对照组,实验组与对照组患者治愈率(92.5%vs 55.0%),反跳率(2.5%vs 15.0%),转院率(5.0%vs 20.0%),死亡率(0.0%vs 10.0%),差异有统计学意义(t=9.752,P=0.000;t=7.607,P=0.000,t=0.246,P=0.807;t=5.342,P=0.000;t=0.123,P=0.919;t=7.843,P=0.000;t=8.630,P=0.000;χ^2=13.341,P=0.000;χ^2=3.914,P=0.048;χ^2=4.114,P=0.043;χ^2=4.211,P=0.041)。结论在急性中毒性肺水肿患者的抢救中,采取东茛菪碱与地塞米松联合治疗,可明显缩短患者治疗起效时间与水肿消失时间,提高临床救治效果。Objective To observe the clinical analysis of the combined treatment of scopolamine and dexamethasone in the rescue of acute toxic pulmonary edema.Methods Convenient selection of 80 patients who were admitted to the hospital recently from January 2016 to December 2018 for diagnosis of acute toxic pulmonary edema and received conventional treatment in combination with east hyosamine and dexamethasone were randomly divided into the observation group and the control group.By observing the treatment onset time,edema disappearance time,blood gas index level and hospital stay before and after treatment,the treatment effect and prognosis of the two groups of patients.Results After treatment group was better than control group,patients with blood gas index level and effect of the experimental group patients,edema disappeared time and hospitalization time significantly less than the control group,experimental group and control group cure rate(92.5%vs 55.0%)patients,bounce rate(2.5%vs 15.0%),transfer rate(5.0%vs 20.0%),mortality(0.0%vs 10.0%),statistically significant difference(t=9.752,P=0.000;t=7.607,P=0.000,t=0.246,P=0.807;t=5.342,P=0.000;t=0.123,P=0.919;t=7.843,P=0.000;t=8.630,P=0.000;χ^2=13.341,P=0.000;χ^2=3.914,P=0.048;χ^2=4.114,P=0.043;χ^2=4.211,P=0.041).Conclusion In the rescue of patients with acute toxic pulmonary edema,the combination of scopolamine and dexamethasone can significantly shorten the onset time of treatment and the disappearance time of edema,and improve the clinical treatment effect.

关 键 词：东茛菪碱 地塞米松 联合治疗 急性中毒性肺水肿 抢救效果 

分 类 号：R595[医药卫生—内科学]