富血小板纤维蛋白联合自体脂肪颗粒移植在面部轮廓修饰中的临床应用  

PRF-mixed autogenous fat granules transplantation for modification of facial contour

作　　者：晏丹[1] 黄泽春[1] 张安利[1] 李帅华[1] 肖瑶[1] 王红梅[1] Yan Dan;Huang Zechun;Zhang Anli;Li Shuaihua;Xiao Yao;Wang Hongmei(Department of Plastic and Cosmetic Surgery,the First People's Hospital of Chenzhou,Chenzhou 423000,China)

机构地区：[1]郴州市第一人民医院整形美容科,423000

出　　处：《中华医学美学美容杂志》2020年第1期51-55,共5页Chinese Journal of Medical Aesthetics and Cosmetology

基　　金：郴州科技局科技发展计划基金(zdyf201842)。

摘　　要：目的分析富血小板纤维蛋白(PRF)联合自体脂肪颗粒移植在面部轮廓修饰中的临床疗效,探讨提高面部移植脂肪保留率的方法。方法将60例入选美容就医者随机分为PRF联合脂肪颗粒移植组(观察组)和单纯脂肪颗粒移植治疗组(对照组),每组30例。根据不同面部轮廓缺陷部位,分别抽取适量的自体脂肪颗粒,并与全血中离心分离的PRF混合或不混合后进行自体移植。结果患者术后6个月外形基本稳定,两组病例面部均较前饱满,轮廓比例更为协调。随访1年,无1例发生脂肪栓塞、感染、坏死等并发症;1次移植后患者满意度在观察组和对照组分别为96.7%和80.0%,差异有统计学意义(P<0.05)。结论采用PRF联合自体脂肪颗粒移植技术,其操作简单,脂肪保留率较单纯移植组明显提高,远期效果稳定,无明显不良反应,1次足够量的移植则可达到较好矫形效果,在面部轮廓修饰和面部年轻化中具有重要的应用价值。Objective To analyze the clinical efficacy of PRF-mixed autogenous fat granules transplantation for facial contour modification,and to discuss the methodology for improving fat preservation rate after facial fat transplantation.Methods 60 cases were divided randomly into two groups with 30 cases each:mixed treatment group of PRF and autologous fat granules(mixed group),and simple autologous fat granules transplantation group(control group).According to the different defect parts of facial contour,the mixture of proper amount of autologous fat granules and PRF harvested from venous blood via once centrifugation separation autologous transplanted to the cases in mixed group,PRF not added to the cases in control group,then the recent and long-term effect,complications,safety,and patient satisfaction were observed.Results The facial shape was stable 6 months after operation,the face of all cases was more full,and facial proportion was more harmonious than before operation.12 months of follow-up study was performed in all 60 cases,there was no fat embolism,infection,necrosis and other complications.The satisfaction rate was 96.7%in mixed group and 80%in control group after primary operation respectively.There were significant differences between the two groups.Conclusions Autologous transplantation of fat granule mixed with PRF has important application value in facial contour modification and facial rejuvenation.It is easy to be operated,and can achieve high fat preservation rate,stable long-term effect and no obvious complication;the cases performed sufficient amount mixture of transplantation can get ideal cosmetic effect.

关 键 词：脂肪颗粒 富血小板纤维蛋白 移植 面部美容 面部年轻化 

分 类 号：R6[医药卫生—外科学]