膀胱残余尿量测定联合IPSS初步筛查糖尿病神经源性膀胱  

Bladder residual urine volume measurement and international prostate symptom score preliminary screening of diabetic neurogenic bladder

作　　者：段丽君[1] 郭洪涛[1] 商书霞[1] 赵军魁[2] 孙秋杰 贾红丽 DUAN Lijun;GUO Hongtao;SHANG Shuxia;ZHAO Junkui;SUN Qiujie;JIA Hongli(Department of Endocrinology,Jizhong Energy Fengfeng Group Hospital,Hebei Province,Handan 056200,China;Department of Critical Medicine,Jizhong Energy Fengfeng Group Hospital,Hebei Province,Handan056200,China;Department of Endoscopy,Jizhong Energy Fengfeng Group Hospital,Hebei Province,Handan 056200,China;Department of Operating Room,Jizhong Energy Fengfeng Group Hospital,Hebei Province,Handan 056200,China)

机构地区：[1]冀中能源峰峰集团有限公司总医院内分泌科,河北邯郸056200 [2]冀中能源峰峰集团有限公司总医院重症医学科,河北邯郸056200 [3]冀中能源峰峰集团有限公司总医院内镜室,河北邯郸056200 [4]冀中能源峰峰集团有限公司总医院手术室,河北邯郸056200

出　　处：《中国医药导报》2020年第12期76-79,共4页China Medical Herald

基　　金：河北省医学科学研究课题(20191176)。

摘　　要：目的探讨2型糖尿病神经源性膀胱初步筛查的方法及可能的影响因素。方法选取2018年1~12月冀中能源峰峰集团有限公司总医院内分泌科住院的2型糖尿病男性患者209例,根据膀胱残余尿量不同分为A组(膀胱残余尿量<50 mL)125例,B组(膀胱残余尿量≥50 mL)84例。比较两组患者的前列腺体积、国际前列腺症状评分(IPSS),入院时随机血糖、糖化血红蛋白、舒张压、收缩压及糖尿病病程情况;采取多元线性回归分析上述观察指标对膀胱余尿量的影响;比较两组糖尿病病程、前列腺体积引起膀胱余尿量增多概率,Pearson检验分析膀胱余尿量与糖尿病病程、糖化血红蛋白及入院随机血糖的相关性。结果与A组比较,B组糖尿病病程长、前列腺体积增大、入院时血糖高(P <0.05),B组排尿问题评分显著高于A组,差异有统计学意义(P <0.05);糖尿病病程≥10年及前列腺体积≥30 mL的患者残余尿量≥50 mL人数显著增加(P <0.05);糖化血红蛋白、糖尿病病程、前列腺体积是膀胱残余尿量增多的危险因素(P <0.05);前列腺体积<30 mL时膀胱残余尿量的多少与糖尿病病程密切相关(r=0.289,P <0.05);前列腺体积增大(≥30 mL)时膀胱残余尿量与糖化血红蛋白、入院随机血糖密切相关(r=0.370、0.381;P <0.05)。结论膀胱余尿量测定联合IPSS可辅助早期筛查糖尿病神经性膀胱,方法简单易行,对于糖尿病病程长、合并前列腺体积增大患者,需及早干预、积极防治。Objective To explore the methods and possible influencing factors of primary screening of neurogenic bladder in type 2 diabetes mellitus. Methods From January to December 2018, 209 male patients with type 2 diabetes were selected from the Department of Endocrinology of Jizhong Energy Fengfeng Group Hospital. According to different bladder residual urine volume, 125 cases were divided into group A(bladder residual urine volume < 50 mL) and 84 cases were divided into group B(bladder residual urine volume ≥50 mL). Prostate volume, international prostate symptom score(IPSS), random blood glucose, glycosylated hemoglobin, diastolic blood pressure, systolic blood pressure and diabetes course were compared between the two groups;the effect of the above observation indexes on bladder residual urine volume was analyzed by multiple regression analysis;the probability of increased bladder residual urine volume caused by diabetes course and prostate volume was compared between the two groups. Pearson test was used to analyze the correlation between bladder residual urine volume and diabetes course, glycosylated hemoglobin and random blood glucose at admission. Results Compared with group A, group B had longer diabetes course, enlarged prostate volume and high blood glucose at admission(P < 0.05). The score of urination problem in group B was significantly higher than that in group A, and the difference was statistically significant(P < 0.05);the number of patients with residual urine ≥50 mL was significantly increased in patients with diabetes course greater than 10 years and prostate volume greater than 30 mL(P < 0.05);glycosylated hemoglobin, duration of diabetes, and prostate volume were risk factors for increased bladder residual urine volume(P< 0.05);when the prostate volume was less than 30 mL, the amount of residual bladder urine was closely related to the course of diabetes(r = 0.289, P < 0.05);when prostate volume increased(≥30 mL), bladder residual urine volume was closely correlated with glycosylated hemoglo

关 键 词：2型糖尿病 膀胱残余尿量 糖尿病神经性膀胱 国际前列腺症状评分 糖化血红蛋白 前列腺增生 

分 类 号：R587.2[医药卫生—内分泌]