综合用药对肺炎支原体感染患儿免疫、血清及睡眠质量的影响  

Effects of Comprehensive Drug Administration on Immunity Serum and Sleep Quality of Children with Mycoplasma Pneumoniae Infection

作　　者：殷世超 YIN Shichao(Bengbu third people′s hospital,Bengbu 233000,China)

机构地区：[1]蚌埠市第三人民医院,蚌埠233000

出　　处：《世界睡眠医学杂志》2020年第2期273-275,共3页World Journal of Sleep Medicine

摘　　要：目的:探讨普米克令舒联用阿奇霉素、孟鲁司特钠对肺炎支原体感染患儿免疫功能、血清因子及睡眠质量的影响。方法:选取2017年11月至2018年11月蚌埠市第三人民医院儿科收治的肺炎支原体感染患儿96例作为研究对象,随机分为对照组与观察组,每组48例。对照组患儿采用阿奇霉素、孟鲁司特钠进行治疗,观察组患儿在对照组的基础上联用普米克令舒治疗,统计整合2组治疗的相关数据指标情况并进行比较。结果:观察组临床症状消失时间均短于对照组,差异有统计学意义(P<0.05);观察组治疗后炎性因子水平明显优于对照组,差异有统计学意义(P<0.05);观察组治疗后免疫功能水平明显优于对照组,差异有统计学意义(P<0.05);观察组治疗后睡眠质量评分明显高于对照组,差异有统计学意义(P<0.05)。结论:小儿肺炎支原体感染的治疗中,采用普米克令舒联用阿奇霉素、孟鲁司特钠可有效缩短临床症状消失时间,患儿免疫功能等指标得到改善,有较高的临床价值。Objective:To investigate the effects of pulmicrine combined with azithromycin and montelukast sodium on immune function,serum factors and sleep quality in children with mycoplasma pneumoniae infection.Methods:A total of 96 children with mycoplasma pneumoniae infection admitted to the department of pediatrics of bengbu third people′s hospital from November 2017 to November 2018 were randomly divided into control group and observation group,with 48 cases in each group.The children in the control group were treated with azithromycin and montelukast sodium.The children in the observation group were treated with pulmicrine on the basis of the control group.The data indicators of the two groups were statistically integrated and compared.Results:The disappearance time of clinical symptoms in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).The levels of inflammatory factors in the observation group were significantly better than those in the control group,with statistically significant differences(P<0.05).After treatment,the level of immune function of the observation group was significantly better than that of the control group,and the difference was statistically significant(P<0.05).The score of sleep quality in the observation group was significantly higher than that in the control group(P<0.05).Conclusion:In the treatment of mycoplasma pneumoniae infection in children,the use of pulmicorrine combined with azithromycin and montelukast sodium can effectively shorten the time of the disappearance of clinical symptoms and improve the immune function of children.

关 键 词：普米克令舒 阿奇霉素 肺炎支原体感染 免疫功能 血清因子 睡眠质量 

分 类 号：R375.2[医药卫生—病原生物学] R338.63[医药卫生—基础医学]