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作 者:马医宗 王斌[1] MA Yizong;WANG Bin(Dept. of Pharmacy, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China)
机构地区:[1]上海交通大学医学院附属新华医院药学部,上海200092
出 处:《中国医院用药评价与分析》2020年第3期347-349,353,共4页Evaluation and Analysis of Drug-use in Hospitals of China
摘 要:目的:了解儿科呼吸道感染用药情况,促进合理用药。方法:抽取2018年4—12月上海交通大学医学院附属新华医院(以下简称“我院”)儿内科门急诊处方6078张,统计小儿呼吸道感染率、抗菌药物使用率、伴发热患儿用药情况以及联合使用、单独使用中成药情况等,并对处方规范性、用药合理性进行分析。结果:6078张儿内科门急诊处方中,诊断为呼吸道感染的处方共5101张,占83.93%;呼吸道感染患儿抗菌药物使用率为77.67%(3962/5101);58.69%(2994/5101)的患儿伴发热;呼吸道感染患儿中成药联合使用率、单独使用率分别为67.71%(3454/5101)、4.65%(237/5101);不合理呼吸道感染处方12张,涉及遴选药品不适宜、药品用法与用量不适宜、重复用药和药品适应证与诊断不符。结论:我院儿科呼吸道感染常用药物为抗菌药物、中成药及辅助用药;处方规范性和用药合理性总体较好,其中抗菌药物使用率较高。临床药师应加强对儿科处方的审核并及时与医师沟通,规范抗菌药物的使用,确保儿童用药安全、有效。OBJECTIVE:To investigate the drug use for pediatric respiratory tract infections,so as to promote the rational use of drugs.METHODS:Totally 6078 pediatric outpatient emergency prescriptions were extracted from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine(hereinafter referred to as“our hospital”)from Apr.to Dec.2018.Statistical analysis was conducted on respiratory infection rate in children,utilization rate of antibiotics,medication status of children with fever and drug combination,use of Chinese patent medicine alone.And standardization of prescription and rationality of medication were analyzed.RESULTS:Of the 6078 pediatric outpatient emergency prescriptions,there were 5101 prescriptions for respiratory tract infections(83.93%).The utilization rate of antibiotics in children with respiratory tract infection was 77.67%(3962/5101).There were 58.69%(2994/5101)of children with fever.The combined utilization rate and the single utilization rate of Chinese patent medicine in children with respiratory tract infection were 67.71%(3454/5101)and 4.65%(237/5101),respectively.There were 12 irrational prescriptions for respiratory tract infection,including inappropriate selection of drugs,inappropriate use and dosage of drugs,repeated drug use,inconsistent indications and diagnosis.CONCLUSIONS:The commonly used drugs for pediatric respiratory infections in our hospital are antibiotics,Chinese patent medicine and adjuvant drugs.Prescription standardization and rationality of medication are generally better,and the use rate of antibiotics is higher.Clinical pharmacists should strengthen the review of pediatric prescriptions and timely communicate with clinicians to standardize the use of antibiotics to ensure the safety and effectiveness of medication for children.
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