细胞胀亡的检测方法  

The detection methods of cellular oncosis

作　　者：潘颖星 黎骊(综述) 薛薇 阳洁(审校)[1] PAN Ying-xing;LI Li(reviewing);XUE Wei;YANG Jie(checking)(School of Pharmacy,Guangxi Medical University,Nanning 530021,Guangxi,China)

机构地区：[1]广西医科大学药学院,南宁530021

出　　处：《医学研究生学报》2020年第5期525-530,共6页Journal of Medical Postgraduates

基　　金：国家自然科学基金(81860649)。

摘　　要：细胞胀亡是一种重要的非凋亡性细胞死亡方式,其特征主要表现为细胞肿胀和细胞核溶解。研究表明,细胞胀亡参与了肿瘤和心血管疾病等的发生发展。选择合适的检测方法是开展细胞胀亡研究的关键,但目前对细胞胀亡的检测方法选择尚缺乏统一定论。因此,文章就细胞胀亡的概念、特点及现有检测方法的原理和优缺点作一综述,为细胞胀亡检测方法的选择提供参考,以促进细胞胀亡相关的研究。Cellular oncosis is an important non-apoptosis mode of cell death characterized by cell swelling and karyolysis.Studies have indicated that cellular oncosis is involved in the progress of tumor and cardiovascular diseases as well as other diseases.The selection of appropriate detection method is the key to the study of cellular oncosis.However,there is still no unified standard of detection methods for cellular oncosis.Therefore,this paper summarizes the concept and characteristics of cellular oncosis,as well as principle,the advantages and disadvantages of existing detection methods,so as to provide reference for the selection of detection methods and promote the research on cellular oncosis.

关 键 词：细胞死亡 细胞胀亡 检测方法 

分 类 号：R33[医药卫生—人体生理学]