纳米光热剂在肿瘤诊断及治疗一体化的研究进展  

Research progress on nano-photothermal agents in integration of tumor diagnosis and treatment

作　　者：刘勤敏(综述) 金观桥(审校)[1] LIU Qin-min(reviewing);JIN Guan-qiao(checking)(Department of Radiology,Guangxi Medical University Cancer Hospital,Nanning 530021,Guangxi,China)

机构地区：[1]广西医科大学附属肿瘤医院医学影像中心,南宁530021

出　　处：《医学研究生学报》2020年第5期531-536,共6页Journal of Medical Postgraduates

基　　金：国家自然科学基金(81260334,81760533)。

摘　　要：光热治疗作为一种新型非侵入性的治疗技术,自20世纪80年代以来发展十分迅速,尤其是在肿瘤治疗方面,有着传统疗法无可替代的作用。当前用于光热治疗的材料主要为各种纳米粒子,以及基于各种纳米粒子设计出来的各种纳米复合材料。由于部分纳米复合材料综合了光热治疗剂及影像学成像对比剂的性能特点,使其在肿瘤诊断及治疗一体化的研究方面发挥了巨大的作用。文章分别从四类纳米治疗剂的理化特性、光学性能以及在光热治疗研究中表现出的优劣势,对近些年来四类纳米光热剂在肿瘤诊断和治疗一体化的实验研究进展进行综述。Photothermal therapy,as a new non-invasive therapy technique,has been developing rapidly since 1980s,especially in tumor therapy.Compared with traditional therapy,it has demonstrated irreplaceable effects.At present,the materials used for photothermal therapy are mainly various nanoparticles as well as various nanocomposites designed based on it.Because some nanocomposites have integrated the properties of photothermal therapeutic agents and imaging contrast agents,they have played an important role in the integrated study of tumor diagnosis and treatment.Based on the physical and chemical properties,optical properties,advantages and disadvantages of the four kinds of nano-therapeutic agents in the study of photothermal therapy,this paper reviews the progress of the experimental research on the integration of the four kinds of nano-photothermal agents in tumor diagnosis and treatment in recent years.

关 键 词：纳米光热剂 肿瘤 光热治疗 成像 

分 类 号：R454[医药卫生—治疗学]