Innovative Light Therapy:1.Biological Effectiveness of Polychromatic Polarized Light Transmitted through Interference,Absorption and Fullerene Filters  

作　　者：Sergiy A.Gulyar Zynaida A.Tamarova 

机构地区：[1]Department of Sensory Signaling,Bogomoletz Institute of Physiology,National Academy of Sciences of Ukraine,Kyiv 401601,Ukraine [2]International Medical Innovation Center Zepter,Kyiv 02152,Ukraine

出　　处：《Journal of US-China Medical Science》2020年第1期27-36,共10页美中医学（英文版）

摘　　要：On the formalin test model,we studied the effect of polychromatic polarized light of the BIOPTRON device equipped with interference filters(red,blue,green)on pain and non-painful behavioral reactions of laboratory animals with a locus of tonic/inflammatory pain.The study(the same for all light variants)was performed on adult white laboratory mice-males weighing 27-32 g.The pain center was caused by subcutaneous injection of 0.3μL of 5%formalin solution in the dorsum of the left hind limb.The intensity of the pain was judged by the duration of the pain reaction(licking of the pain locus)for consecutive 10 minutes and for the entire observation period(60 minutes).The light source was the BIOPTRON-compact,equipped with a halogen lamp and a Brewster polarizer.Light was applied to the pain locus immediately after formalin injection for 10 minutes.The distance from the filter to the skin surface was 5 cm,and the diameter of the light spot was reduced to 5 mm.The control was a group of animals with a similar pain effect,but without light application.Processing of experimental data was carried out on a computer using special programs.It was found that polychromatic light obtained after conversion by interference filters as monochromatic red,blue or green statistically significantly(p<0.001;p<0.05;p<0.05)reduced the pain.The duration of the pain response during 60 minutes of observation reduced to 341±93 s(red filter),435.4±37.1 s(blue filter)or 343.6±65.8 s(green filter)versus 566.2±47 s in the control(without light application).If the duration of the pain response in the control was taken as 100%,then after 10 minutes of exposure to the pain area with monochromatic polarized light obtained after conversion by interference filters,the pain was 60%,77%and 61%,respectively.Based on these data,the red and green filters turned out to be the most effective,and the least—blue.The duration of the pain response in the group that received a 10-minute exposure to the locus of pain by light passing through the fullerene filt

关 键 词：Polychromatic polarized light Bioptron device pain FORMALIN test ANALGESIA INTERFERENCE FILTER ABSORPTION filter fullerene FILTER 

分 类 号：R24[医药卫生—中医临床基础]