南京市2013-2017年HIV合并梅毒感染流行特征和检测策略分析  

Analysis on epidemiological characteristics and detection strategies of HIV combined with syphilis infection in Nanjing City from 2013 to 2017

作　　者：吴咏梅[1] 许文炯[1] 王燕[1] 董潇潇[1] 杜雪飞[1] WU Yongmei;XU Wenjiong;WANG Yan;DONG Xiaoxiao;DU Xuefei(Nanjing Center for Disease Control and Prevention,Jiangsu210003,China)

机构地区：[1]南京市疾病预防控制中心,江苏210003

出　　处：《医学动物防制》2020年第4期384-387,390,共5页Journal of Medical Pest Control

基　　金：江苏省卫生计生委2014-2015年度预防医学科研课题(Y2015002)。

摘　　要：目的了解南京市2013-2017年HIV合并梅毒感染者流行病学特征,并分析其相关因素。方法对南京市2013-2017年在艾滋病确证实验室报告的655例HIV合并梅毒感染者资料进行整理和分析,主要包括一般人口学特征、感染途径和样本来源。结果合并感染例数总体呈上升趋势的群体有:男性人群,19~40岁和61岁以上年龄组,未婚,文化程度在大专及以上。感染途径以同性性传播途径为主(69.9%),样本来源以医疗机构为主(71.2%)。通过同性性传播合并梅毒的感染率显著大于通过异性性传播合并梅毒的感染率(P<0.05)。单因素分析显示,性别、年龄、户籍、职业、婚姻状况、文化程度、感染途径及样本来源与合并梅毒感染相关(P<0.05)。多因素Logistic回归分析显示,文化程度(P=0.010)和婚姻状况(P=0.003)与合并梅毒感染相关。结论加大HIV合并梅毒感染检测力度和增加检测频率,加强实验室早期检测能力建设,以建立南京市HIV合并梅毒感染检测策略。Objective To get an insight into the epidemiological characteristics of HIV patients with syphilis in Nanjing from 2013 to 2017,and to analyze the related factors.Methods The data of 655 cases of HIV combined with syphilis reported in AIDS confirmation laboratory in Nanjing City from 2013 to 2017 were collated and analyzed,including general demographic characteristics,infection routes and sample sources.Results The total number of co-infected cases is generally increasing:male population,19~40 years old and over 61 years old group,unmarried,with a college degree or above.The main route of infection was homosexual transmission(69.9%),and the main sources of samples were medical institutions(71.2%).The infection rate of syphilis by homosexual transmission was significantly higher than that by heterosexual transmission(P<0.05).Univariate analysis showed that gender,age,household registration,occupation,marital status,education level,infection route and source of samples were associated with syphilis infection(P<0.05).Multivariate Logistic regression analysis showed that education level(P=0.010)and marital status(P=0.003)were associated with syphilis infection.Conclusion It is necessary to increase the intensity and frequency of HIV infection combined with syphilis detection,and strengthen the capacity building of laboratory early detection to establish a detection strategy of HIV infection combined with syphilis in Nanjing.

关 键 词：HIV 梅毒 流行病学 合并感染 单因素分析 多因素分析 实验室检测 

分 类 号：R512.91[医药卫生—内科学] R759.1[医药卫生—临床医学]