机构地区:[1]中国中医科学院广安门医院南区外科,北京102618
出 处:《医学综述》2020年第9期1847-1850,1855,共5页Medical Recapitulate
摘 要:目的探讨中药联合微波治疗慢性前列腺炎(CP)的临床疗效。方法选择2013年1月至2015年8月中国中医科学院广安门医院南区外科门诊收治的120例CP患者为研究对象,依据随机数字法分为中药组、西药联合微波组、中药联合微波组,各40例。中药组采用活血利湿方治疗,煎煮滤汁150 m L,分早、晚两次服用,每日1剂;西药联合微波组采用西药(甲磺酸左氧氟沙星、盐酸特拉唑嗪)联合前列腺微波治疗,微波强度为10 W,保持30 min,每周2次;中药联合微波组在中药治疗组基础上联合前列腺微波治疗,三组均连续治疗8周。比较各组的临床疗效,治疗前后CP中医证候评分、美国国立卫生院前列腺炎症状评分(NIH-CPSI)以及安全性。结果中药组、西药联合微波组、中药联合微波组总有效率分别为77. 5%(31/40)、57. 5%(23/40)、87. 5%(35/40),中药联合微波组临床疗效优于中药组、西药联合微波组(P <0. 05)。三组间中医症状评分、NIH-CPSI评分比较差异有统计学意义(P <0. 05);治疗4周、8周,三组中医症状评分、NIH-CPSI评分呈下降趋势,且各时点间中药联合微波组的中医症状评分、NIH-CPSI评分低于中药组和西药联合微波组,各指标时点间、组间和时点间交互作用差异有统计学意义(P <0. 05)。中药组胃肠反应3例(7. 5%),西药联合微波组肾损伤2例、胃肠反应2例,不良反应发生率为10. 0%,中药联合微波组肾功能损伤1例(2. 5%),三组不良反应发生率比较差异无统计学意义(P> 0. 05)。结论中药联合微波治疗CP可明显改善患者中医症候评分及NIH-CPSI评分,临床疗效较好。Objective To investigate the clinical effect of traditional Chinese medicine combined with microwave on chronic prostatitis( CP). Methods From Jan. 2013 to Aug. 2015,120 CP patients admitted to the Southern Surgery Clinic of Guang’anmen Hospital of the Chinese Academy of Chinese Medical Sciences were included in the study. They were divided into a traditional Chinese medicine group,a western medicine combined microwave group,and a traditional Chinese medicine combined microwave group based on random number method,40 cases each. The traditional Chinese medicine group was treated with Huoxue Lishi decoction,150 m L of decoction juice was taken in the morning and evening daily,and the western medicine combined microwave group used western medicine( levofloxacin mesylate,terazosin hydrochloride)combined with prostate microwave treatmentat the intensity of 10 W for 30 minutes,twice a week;the traditional Chinese medicine combined microwave group was treated with the prostate microwave treatment on the basis of the traditional Chinese medicine group;each group was treated for 8 weeks. The clinical efficacy of each group was compared,the CP traditional Chinese medicine syndrome score,the National Institutes of Health chronic prostatitis symptom index( NIH-CPSI)before and after treatment,and the safety were compared. Results The total effective rate of the traditional Chinese medicine group,western medicine combined microwave group,and traditional Chinese medicine combined microwave group was 77. 5%( 31/40),57. 5%( 23/40),and 87. 5%( 35/40) respectively,traditional Chinese medicine combined microwave group better than the traditional Chinese medicine group and western medicine combined microwave group( P <0. 05). There was a statistically significant difference in traditional Chinese medicine symptom scores and NIH-CPSI scores among the three groups( P < 0. 05);After 4 weeks and 8 weeks treatment,the traditional Chinese medicine symptom scores and NIH-CPSI scores of the three groups showed a downward trend,and at each
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