一种咀嚼片型润喉糖的制备及质量评价  

Preparation and Evaluation of Chewable Tablets that Has Function of Clear and Nourish Throat

作　　者：刘晓庆 曾薇薇[2] 赵梅珍 王翠红 夏胜利 LIU Xiaoqing;ZENG Weiwei;ZHAO Meizhen;WANG Cuihong;XIA Shengli(Shanghai University of Medicine&Health Sciences Affiliated Zhoupu Hospital,Shanghai 201318,China;Shanghai University of Traditional Chinese Medicine Affiliated Shuguang Hospital,Shanghai 201203,China)

机构地区：[1]上海健康医学院附属周浦医院,上海201318 [2]上海中医药大学附属曙光医院,上海201203

出　　处：《农产品加工》2020年第8期15-17,共3页Farm Products Processing

基　　金：浦东新区中医药研发专项资助项目(PDZYYFCX-201818);浦东新区卫生和计划生育委员会领先人才培养计划资助项目(PWR12018-09)。

摘　　要：以《伤寒论》中甘桔汤配方为基础,引入药食同源的玉竹、乌梅和罗汉果进行重新组方,采用单因素试验法优化处方,通过湿法制粒压片工艺,以片重差异、组织状态、口感和色泽为指标进行综合评分,制备润喉咀嚼片。结果表明,当处方中稠膏与微晶纤维素和甘露醇的的质量比为1∶2∶3,硬脂酸镁添加量为0.1%时,所得润喉糖综合评分最高。所得处方可制得形态完整、表面光滑、断面紧密、色泽均匀、咀嚼度良好的润喉糖,为进一步工业化生产提供参考。Based on the licorice and platycodon decoction in treatise on febrile diseases,polygonatum odoratum,dark plum and momordica grosvenori were added to form a new soothe throats prescription to make a natural,good taste chewable tablets.The formulation was optimized by single factor experiment.Through the wet granulation tablet pressing process,the tablet quality was evaluated by the weight difference,tissue state,taste and color.The best formulation were as follows:the mass ratio of extract to microcrystalline cellulose and mannitol was 1∶2∶3 and the content of magnesium stearate was 0.1%.The best formulation could make the chewable tablets which had complete morphology,smooth surface,compact section,uniform color and good chewability,and provide reference for further industrialized production.

关 键 词：甘桔汤 咀嚼片 润喉糖 清咽利嗓 

分 类 号：R283[医药卫生—中药学]