杜仲骨保护的作用机制研究进展  

Research Progress on Mechanism of Duzhong(Eucommia ulmoides Oliver) in Bone Protection

作　　者：邢蕴蕴 王健英[1,2] 潘颖宜 陈晓云[1,2] 袁颖 XING Yunyun;WANG Jianying;PAN Yingyi;CHEN Xiaoyun;YUAN Ying(Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 2O0032,China)

机构地区：[1]上海中医药大学,上海201203 [2]上海中医药大学附属龙华医院,上海200032

出　　处：《中华中医药学刊》2020年第3期92-95,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金(81773922);上海市自然科学基金(19ZR1452000);第三批上海中医药大学中青年骨干教师教学能力提升计划(A1-U182050102060508).

摘　　要：杜仲是我国传统中药材,其补肝肾、强筋骨的作用一直以来被人们应用。除骨质疏松存在骨代谢失衡外,类风湿性关节炎、骨关节炎、强直性脊柱炎都存在着炎症性骨破坏的特点。通过查阅近年来国内外杜仲研究相关文献,从骨代谢平衡、抗炎作用2个方面介绍杜仲抑制骨破坏,促进骨保护的作用机制,为杜仲强筋健骨作用提供现代研究支持。Duzhong(Eucommia ulmoides Oliver) is a traditional Chinese medicinal material in China and its role in nourishing liver, kidney and strengthening muscles and bones has been applied all along. Except for the imbalance of bone metabolism in osteoporosis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis all have the characteristics of inflammatory bone destruction. By consulting the literature of Duzhong(Eucommia ulmoides Oliver) at home and abroad in recent years, this paper introduced the mechanism of inhibiting bone destruction and promoting bone protection in two aspects, including the balance of bone metabolism and anti-inflammatory effect. It provides modern research support for the role of Duzhong(Eucommia ulmoides Oliver) in strengthening muscles and bones.

关 键 词：杜仲 炎症性骨破坏 骨代谢 炎症因子 

分 类 号：R282.71[医药卫生—中药学]