济南市新型冠状病毒肺炎密切接触者隔离医学观察情况分析与评价  

Analysis and evaluation of the isolation medicine observation for close contacts of Coronavirus disease 2019 in Jinan City

作　　者：杨丽[1] 李战[1] 刘晓雪[1] 焦海涛[1] 周林[1] 刘庆皆 刘铁诚[1] 耿兴义[1] YANG Li;LI Zhan;LIU Xiaoxue;JIAO Haitao;ZHOU Lin;LIU Qingjie;LIU Tiecheng;GENG Xingyi(Jinan Municipal Center for Disease Control and Prevention,Jinan 250021,Shandong,China)

机构地区：[1]济南市疾病预防控制中心,山东济南250021

出　　处：《山东大学学报（医学版）》2020年第4期12-16,共5页Journal of Shandong University:Health Sciences

摘　　要：目的分析济南市新型冠状病毒肺炎(COVID-19)密切接触者隔离医学观察情况。方法收集2020年1月24日至3月1日济南市COVID-19处置期间流行病学调查资料,筛选出因新型冠状病毒肺炎(COVID-19)被隔离的密切接触者信息,采用Excel 2007和SPSS16.0软件对数据资料进行整理与分析。结果共对1455例COVID-19密切接触者进行隔离医学观察,从中共检出28例2019-nCOV感染者,包括25例确诊COVID-19病例和3例阳性无症状者,罹患率为1.92%。1455例COVID-19密切接触者主要分布在历下区(40.69%)、历城区(16.98%)及市中区(8.38%)。与原发病例不同关系的密切接触者的2019-nCOV检出率不同(χ^2=180.34,P<0.001),其中与原发病例为亲属关系的密切接触者罹患率最高(15.38%)。2019-nCOV感染的密切接触者共有13例原发病例,其中5例(38.46%)有武汉旅行史,1例(7.69%)有湖北旅行史,3例(23.08%)有除湖北外外地旅行史,其余4例(30.77%)无外地旅行史。济南市管理的密切接触者中23例发病,其中8例(34.78%)在密切观察期前已发病,发病至隔离的时间间隔中位数为5 d。15例(65.22%)在隔离观察期内发病,时间间隔中位数为3 d。23例COVID-19密切接触者医学观察期至确诊时间中位数2 d,发病至确诊时间中位数为3 d。济南市管理的密切接触者中23例发病,其中17例(73.91%)临床严重程度为普通型患者,6例(23.09%)为轻型患者。结论COVID-19病例密切接触者中存在阳性无症状者;应针对重点地区输入人员及密切接触者进行筛查,尽早采取综合防控措施;加强高危人群居家隔离的个人防护措施。Objective To analyze the isolation medicine observation for close contacts of Coronavirus disease 2019(COVID-19)in Jinan City.Methods All information of close contacts who were isolated due to COVID-19 was collected from the epidemiological survey during the epidemic of COVID-19 in Jinan City from January 24 to March 1,2020.The softwares of Excel 2016 and SPSS16.0 were used to sort and analyze data.Results A total of 1455 close contacts were isolated for medical observation.A total of 28 cases of 2019-nCOV infection were detected,including 25 cases of confirmed COVID-19 and 3 cases of positive asymptomatic.The attack rate was 1.92%.1455 close contacts were mainly distributed in Lixia District(40.69%),Licheng District(16.98%)and Shizhong District(8.38%).The detection rate of 2019-nCOV was different among close contacts who had a different relationship with the primary case(χ^2=180.34,P<0.001),among which close-connected cases had the highest incidence of close contacts(15.38%).There were 13 primary cases of close contacts of 2019-nCOV infection,of which 5(38.46%)had a travel history in Wuhan City,1(7.69%)had a travel history in Hubei province,and 3(23.08%)had traveled outside Hubei Province,the remaining 4 cases(30.77%)had no history of field travel.There were 23 of the close contacts who were managed by Jinan City developed disease,of which 8(34.78%)had developed disease before the close observation period,and the median time interval from onset to isolation was 5 days.There were 15 patients(65.22%)who developed disease during the isolation observation period with a median interval of 3 days.The median time of 23 close contacts from the beginning of the medical observation period to the diagnosis was 2 days,and the median time from onset to diagnosis was 3 days.There were 23 of the close contacts who were managed by Jinan City developed disease,of which 17 patients(73.91%)was ordinary type,and 6 patients(23.09%)were mild.Conclusion There are positive and asymptomatic persons in close contact with 2019-nCOV infec

关 键 词：新型冠状病毒肺炎 密切接触者 隔离医学观察 罹患率 效果评价 

分 类 号：R181.3[医药卫生—流行病学]